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A Rare Tumor of Clivus Masquerading as Pituitary Adenoma

Giant cell tumors (GCT) are generally benign, commonly affecting young adults, with a slight preponderance in females. They are locally aggressive with a high rate of local recurrence. Most of them are found in the epiphysis of long bones, making the base of the skull a rare site. We report the case...

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Autores principales: Singh, Swati, Mankotia, Dipanker Singh, Shankar, Kepeemadam Balasubramanyam, Siraj, Fouzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869290/
https://www.ncbi.nlm.nih.gov/pubmed/33708696
http://dx.doi.org/10.4103/ajns.AJNS_188_20
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author Singh, Swati
Mankotia, Dipanker Singh
Shankar, Kepeemadam Balasubramanyam
Siraj, Fouzia
author_facet Singh, Swati
Mankotia, Dipanker Singh
Shankar, Kepeemadam Balasubramanyam
Siraj, Fouzia
author_sort Singh, Swati
collection PubMed
description Giant cell tumors (GCT) are generally benign, commonly affecting young adults, with a slight preponderance in females. They are locally aggressive with a high rate of local recurrence. Most of them are found in the epiphysis of long bones, making the base of the skull a rare site. We report the case of a 35-year-old female, who presented with neurological symptoms of headache and diplopia. On magnetic resonance imaging, a space-occupying lesion was discovered in the clivus. Histopathology was diagnostic of a GCT. GCT arising from the clivus is extremely uncommon, with about 15 cases published in the literature. The present case highlights the rarity of this tumor and contributes to the existing literature with analysis and evaluation of the management strategies and prognosis.
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spelling pubmed-78692902021-03-10 A Rare Tumor of Clivus Masquerading as Pituitary Adenoma Singh, Swati Mankotia, Dipanker Singh Shankar, Kepeemadam Balasubramanyam Siraj, Fouzia Asian J Neurosurg Case Report Giant cell tumors (GCT) are generally benign, commonly affecting young adults, with a slight preponderance in females. They are locally aggressive with a high rate of local recurrence. Most of them are found in the epiphysis of long bones, making the base of the skull a rare site. We report the case of a 35-year-old female, who presented with neurological symptoms of headache and diplopia. On magnetic resonance imaging, a space-occupying lesion was discovered in the clivus. Histopathology was diagnostic of a GCT. GCT arising from the clivus is extremely uncommon, with about 15 cases published in the literature. The present case highlights the rarity of this tumor and contributes to the existing literature with analysis and evaluation of the management strategies and prognosis. Wolters Kluwer - Medknow 2020-12-21 /pmc/articles/PMC7869290/ /pubmed/33708696 http://dx.doi.org/10.4103/ajns.AJNS_188_20 Text en Copyright: © 2020 Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Singh, Swati
Mankotia, Dipanker Singh
Shankar, Kepeemadam Balasubramanyam
Siraj, Fouzia
A Rare Tumor of Clivus Masquerading as Pituitary Adenoma
title A Rare Tumor of Clivus Masquerading as Pituitary Adenoma
title_full A Rare Tumor of Clivus Masquerading as Pituitary Adenoma
title_fullStr A Rare Tumor of Clivus Masquerading as Pituitary Adenoma
title_full_unstemmed A Rare Tumor of Clivus Masquerading as Pituitary Adenoma
title_short A Rare Tumor of Clivus Masquerading as Pituitary Adenoma
title_sort rare tumor of clivus masquerading as pituitary adenoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869290/
https://www.ncbi.nlm.nih.gov/pubmed/33708696
http://dx.doi.org/10.4103/ajns.AJNS_188_20
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