Cargando…

Crystallographic and spectroscopic characterization of 2-[(7-acetyl-4-cyano-6-hydroxy-1,6-dimethyl-8-phenyl-5,6,7,8-tetrahydroisoquinolin-3-yl)sulfanyl]-N-phenylacetamide

In the title molecule, C(28)H(27)N(3)O(3)S, the heterocyclic portion of the tetrahydroisoquinoline unit is planar and an intramolecular N—H⋯N hydrogen bond and a C—H⋯π(ring) interaction help to determine the overall conformation. In the crystal, a layer structure with the layers parallel to (1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Al-Taifi, Elham A., Maraei, Islam S., Bakhite, Etify A., Demirtas, Güneş, Mague, Joel. T., Mohamed, Shaaban K., Ramli, Youssef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2021
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869536/ https://www.ncbi.nlm.nih.gov/pubmed/33614138 http://dx.doi.org/10.1107/S2056989021000372

Ejemplares similares

Crystal structure and Hirshfeld surface analysis of 2-{[7-acetyl-4-cyano-6-hydroxy-8-(4-methoxyphenyl)-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}acetic acid ethyl ester
por: Al-Taifi, Elham A., et al.
Publicado: (2022)

Crystal structure and Hirshfeld surface analysis of 2-{[7-acetyl-4-cyano-6-hydroxy-8-(4-methoxyphenyl)-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}-N-phenylacetamide
por: Sayed, Eman M., et al.
Publicado: (2021)

Crystal structure and Hirshfeld surface analysis of 2-{[7-acetyl-8-(4-chlorophenyl)-4-cyano-6-hydroxy-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}-N-(4-chlorophenyl)acetamide
por: Akkurt, Mehmet, et al.
Publicado: (2021)

(Naphthalen-1-yl){2-[(5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]phenyl}methanone
por: Kanchanadevi, J., et al.
Publicado: (2013)

Nitrophenyl-Group-Containing Heterocycles. I. Synthesis, Characterization, Crystal Structure, Anticancer Activity, and Antioxidant Properties of Some New 5,6,7,8-Tetrahydroisoquinolines Bearing 3(4)-Nitrophenyl Group
por: Sayed, Eman M., et al.
Publicado: (2022)

Crystal structure and Hirshfeld surface analysis of ethyl 2-({5-acetyl-3-cyano-6-methyl-4-[(E)-2-phenylethenyl]pyridin-2-yl}sulfanyl)acetate
por: Al-Waleedy, Safiyyah A. H., et al.
Publicado: (2021)

4-[3-(Trifluoromethyl)phenyl]-5,6,7,8-tetrahydrocinnolin-3(2H)-one
por: Wang, Xin, et al.
Publicado: (2008)

2-Methyl-1,2,3,4-tetrahydroisoquinolin-6-yl N-phenylcarbamate
por: Zhang, Qi-Hong, et al.
Publicado: (2009)

Crystal structure of ethyl 3-amino-6-methyl-2-[(4-methylphenyl)carbamoyl]-4-[(E)-2-phenylethenyl]thieno[2,3-b]pyridine-5-carboxylate monohydrate
por: Mague, Joel T., et al.
Publicado: (2016)

8-(4-Chlorobenzylidene)-4-(4-chlorophenyl)-2-phenyl-5,6,7,8-tetrahydroquinoline
por: Jian, Fangfang, et al.
Publicado: (2010)

Synthesis, Characterization, and Crystal Structure of Some New Tetrahydroisoquinolines and Related Tetrahydrothieno[2,3-c]isoquinolines
por: Marae, Islam S., et al.
Publicado: (2021)

2-(4,6-Dimethylpyrimidin-2-ylsulfanyl)-N-phenylacetamide
por: Gao, Li-Xin, et al.
Publicado: (2008)

2-Amino-7,7-dimethyl-5-oxo-4-[3-(trifluoromethyl)phenyl]-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
por: Kant, Rajni, et al.
Publicado: (2013)

2-[(1R,3S)-6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinolin-3-yl]-4-phenyl-1,3-thiazole
por: Pawar, Sunayna, et al.
Publicado: (2011)

Tris(dibenzoylmethanido-κ(2) O,O′)[(6S,8S)-(+)-7,7-dimethyl-3-(2-pyridyl)-5,6,7,8-tetrahydro-6,8-methanoisoquinoline-κ(2) N,N′]gadolinium(III)
por: Li, Xi-Li, et al.
Publicado: (2009)

3-Phenyl-1-[2-(3-phenylisoquinolin-1-yl)diselanyl]isoquinoline
por: Hathwar, Venkatesha R., et al.
Publicado: (2008)

{(1R,3S)-2-Benzyl-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinolin-3-yl}diphenylmethanol
por: Naicker, Tricia, et al.
Publicado: (2010)

[(1R,3S)-6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinolin-3-yl]methanol 2.33-hydrate
por: Chakka, Sai Kumar, et al.
Publicado: (2011)

Tris(dibenzoylmethanido-κ(2) O,O′)[(6R,8R)-(−)-7,7-dimethyl-3-(2-pyridyl)-5,6,7,8-tetrahydro-6,8-methanoisoquinoline-κ(2) N,N′]terbium(III)
por: Chen, Lei-Qi, et al.
Publicado: (2009)

3,6-Dimethyl-1-phenyl-4-(2-thienyl)-8-(2-thienylmethylene)-5,6,7,8-tetrahydro-1H-pyrazolo[3,4-b][1,6]naphthyridine
por: Peng, Juhua, et al.
Publicado: (2009)

3-Bromo-2-[4-(methylsulfanyl)phenyl]-5,6,7,8-tetrahydro-1,3-benzothiazolo[3,2-a]imidazole
por: Bunev, Alexander S., et al.
Publicado: (2014)

2-Amino-4-[4-(dimethylamino)phenyl]-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
por: Qiao, Yan, et al.
Publicado: (2011)

5,6,7,8-Tetrahydroquinolin-8-one
por: Lipińska, Teodozja M., et al.
Publicado: (2011)

Crystal structure and Hirshfeld surface analysis of 5-acetyl-3-amino-6-methyl-N-phenyl-4-[(E)-2-phenylethenyl]thieno[2,3-b]pyridine-2-carboxamide
por: Mohamed, Shaaban K., et al.
Publicado: (2022)

(1S,3S)-Methyl 6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
por: Naicker, Tricia, et al.
Publicado: (2011)

7-[(Morpholin-4-yl)(phenyl)methyl]quinolin-8-ol
por: Novina, J. Josephine, et al.
Publicado: (2012)

2-Amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
por: Wang, Xiaoli
Publicado: (2011)

2-Phenyl-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]benzothiazole
por: Bunev, Alexander S., et al.
Publicado: (2014)

2-(2-Chlorophenyl)-2-oxo-N-phenylacetamide
por: Dai, Jing, et al.
Publicado: (2011)

(4R,7S)-2-Amino-4-(3,4-dimethoxyphenyl)-5-oxo-7-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile monohydrate
por: Sun, Rong, et al.
Publicado: (2012)

1-(4-Chlorophenyl)-2-[(3-phenylisoquinolin-1-yl)sulfanyl]ethanone
por: Manivel, P., et al.
Publicado: (2009)

(S)-4-Phenyl-2-(1,2,3,4-tetrahydroisoquinolin-3-yl)-1,3-thiazole
por: Pawar, Sunayna, et al.
Publicado: (2011)

Orthorhombic polymorph of (6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)methanol
por: Elkhamlichi, Aouicha, et al.
Publicado: (2011)

4-(4-Methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydrochromene-2,5-dione
por: Shi, Hao
Publicado: (2009)

3-(5,6,7,8-Tetrahydro-2-naphthyl)isobenzofuran-1(3H)-one
por: Kitamura, Chitoshi, et al.
Publicado: (2008)

2-(Dibutylamino)-3-(4-fluorophenyl)-5,6,7,8-tetrahydro-7-methyl-6,8-diphenylpyridine[3′,4′:2,3]thieno[5,4-d]pyrimidin-4(3H)-one
por: Zeng, Guo-ping, et al.
Publicado: (2008)

1-(3-Phenylisoquinolin-1-yl)hydrazine
por: Manivel, P., et al.
Publicado: (2008)

(3-Ethyl-6,7-dimethoxynaphthalen-1-yl)(phenyl)methanone
por: Sakthivel, Karuppusamy, et al.
Publicado: (2012)

[6-(Furan-2-yl)-7-nitro-2,3,4,6,7,8-hexahydro-1H-pyrido[1,2-a]pyrimidin-9-yl](phenyl)methanone
por: Zhang, Wen-Feng, et al.
Publicado: (2013)

4-{Phenyl[4-(6-phenyl-2,2′-bipyridin-4-yl)phenyl]amino}benzaldehyde
por: Zhang, Yu-yang, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_8cd58hppcu7tdbjfcttp14gtqi