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Efficient Tissue Clearing and Multi-Organ Volumetric Imaging Enable Quantitative Visualization of Sparse Immune Cell Populations During Inflammation

Spatial information of cells in their tissue microenvironment is necessary to understand the complexity of pathophysiological processes. Volumetric imaging of cleared organs provides this information; however, current protocols are often elaborate, expensive, and organ specific. We developed a simpl...

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Detalles Bibliográficos
Autores principales: Hofmann, Julian, Gadjalova, Iana, Mishra, Ritu, Ruland, Jürgen, Keppler, Selina J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869862/
https://www.ncbi.nlm.nih.gov/pubmed/33569052
http://dx.doi.org/10.3389/fimmu.2020.599495