Memantine protects blood–brain barrier integrity and attenuates neurological deficits through inhibiting nitric oxide synthase ser(1412) phosphorylation in intracerebral hemorrhage rats: involvement of peroxynitrite-related matrix metalloproteinase-9/NLRP3 inflammasome activation

Memantine has demonstrated beneficial effects on several types of brain insults via therapeutic mechanisms mainly related to its activity as a receptor antagonist of N-methyl-d-aspartate. However, the influences of memantine on intracerebral hemorrhage (ICH) remain obscure. This research probed into...

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Detalles Bibliográficos
Autores principales: Chen, Xiaowei, Xiang, Xu, Xie, Teng, Chen, Zhijun, Mou, Yu, Gao, Zixu, Xie, Xun, Song, Min, Huang, Hui, Gao, Ziyun, Chen, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Cellular, Molecular and Developmental Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870044/
https://www.ncbi.nlm.nih.gov/pubmed/33470757
http://dx.doi.org/10.1097/WNR.0000000000001577

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