Cargando…

Multi-omic modelling of inflammatory bowel disease with regularized canonical correlation analysis

BACKGROUND: Personalized medicine requires finding relationships between variables that influence a patient’s phenotype and predicting an outcome. Sparse generalized canonical correlation analysis identifies relationships between different groups of variables. This method requires establishing a mod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Revilla, Lluís, Mayorgas, Aida, Corraliza, Ana M., Masamunt, Maria C., Metwaly, Amira, Haller, Dirk, Tristán, Eva, Carrasco, Anna, Esteve, Maria, Panés, Julian, Ricart, Elena, Lozano, Juan J., Salas, Azucena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870068/ https://www.ncbi.nlm.nih.gov/pubmed/33556098 http://dx.doi.org/10.1371/journal.pone.0246367

Ejemplares similares

Intestinal Inflammation Modulates the Epithelial Response to Butyrate in Patients With Inflammatory Bowel Disease
por: Ferrer-Picón, Elena, et al.
Publicado: (2020)

Integrated microbiota and metabolite profiles link Crohn’s disease to sulfur metabolism
por: Metwaly, Amira, et al.
Publicado: (2020)

Dissecting Common and Unique Effects of Anti-α4β7 and Anti-Tumor Necrosis Factor Treatment in Ulcerative Colitis
por: Veny, Marisol, et al.
Publicado: (2020)

Differences in Peripheral and Tissue Immune Cell Populations Following Haematopoietic Stem Cell Transplantation in Crohn’s Disease Patients
por: Corraliza, Ana M, et al.
Publicado: (2019)

Generation of human colon organoids from healthy and inflammatory bowel disease mucosa
por: Dotti, Isabella, et al.
Publicado: (2022)

A Novel Strategy to Study the Invasive Capability of Adherent-Invasive Escherichia coli by Using Human Primary Organoid-Derived Epithelial Monolayers
por: Mayorgas, Aida, et al.
Publicado: (2021)

Diet prevents the expansion of segmented filamentous bacteria and ileo-colonic inflammation in a model of Crohn’s disease
por: Metwaly, Amira, et al.
Publicado: (2023)

Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease
por: Garrido-Trigo, Alba, et al.
Publicado: (2023)

Endoscopic response to tumor necrosis factor inhibitors predicts long term benefits in Crohn’s disease
por: Alfaro, Ignacio, et al.
Publicado: (2019)

An RORγt Oral Inhibitor Modulates IL-17 Responses in Peripheral Blood and Intestinal Mucosa of Crohn's Disease Patients
por: Bassolas-Molina, Helena, et al.
Publicado: (2018)

Predictors of bowel damage in the long-term progression of Crohn’s disease
por: Fernández-Clotet, Agnes, et al.
Publicado: (2022)

Usefulness of Transcriptional Blood Biomarkers as a Non-invasive Surrogate Marker of Mucosal Healing and Endoscopic Response in Ulcerative Colitis
por: Planell, Núria, et al.
Publicado: (2017)

Randomized Controlled Trial Substudy of Cell-specific Mechanisms of Janus Kinase 1 Inhibition With Upadacitinib in the Crohn’s Disease Intestinal Mucosa: Analysis From the CELEST Study
por: Aguilar, Daniel, et al.
Publicado: (2021)

Epithelial IL-1R2 acts as a homeostatic regulator during remission of ulcerative colitis
por: Mora-Buch, R, et al.
Publicado: (2016)

Microbial Signals Link Westernized Diet to Metabolic Inflammation: More Evidence to Resolve Controversies
por: Metwaly, Amira, et al.
Publicado: (2019)

Fecal Calprotectin for Small Bowel Crohn’s Disease: Is It a Cutoff Issue?
por: Romero-Mascarell, Cristina, et al.
Publicado: (2022)

Alterations in the epithelial stem cell compartment could contribute to permanent changes in the mucosa of patients with ulcerative colitis
por: Dotti, Isabella, et al.
Publicado: (2017)

Canonical correlation analysis for multi-omics: Application to cross-cohort analysis
por: Jiang, Min-Zhi, et al.
Publicado: (2023)

Pyrcca: Regularized Kernel Canonical Correlation Analysis in Python and Its Applications to Neuroimaging
por: Bilenko, Natalia Y., et al.
Publicado: (2016)

Experimental and genetic evidence for the impact of CD5 and CD6 expression and variation in inflammatory bowel disease
por: Casadó-Llombart, Sergi, et al.
Publicado: (2022)

Multi-omic data integration enables discovery of hidden biological regularities
por: Ebrahim, Ali, et al.
Publicado: (2016)

Regularization and grouping -omics data by GCA method: A transcriptomic case
por: Piwowar, Monika, et al.
Publicado: (2018)

Modeling microbiota-associated human diseases: from minimal models to complex systems
por: Aguanno, Doriane, et al.
Publicado: (2022)

A whitening approach to probabilistic canonical correlation analysis for omics data integration
por: Jendoubi, Takoua, et al.
Publicado: (2019)

Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review)
por: Katoh, Masaru
Publicado: (2017)

A quadratically regularized functional canonical correlation analysis for identifying the global structure of pleiotropy with NGS data
por: Lin, Nan, et al.
Publicado: (2017)

Multi-Omics Data Fusion for Cancer Molecular Subtyping Using Sparse Canonical Correlation Analysis
por: Qi, Lin, et al.
Publicado: (2021)

Properties and kinetics of microRNA regulation through canonical seed sites
por: Chen, Jerry S, et al.
Publicado: (2015)

Group Lasso Regularized Deep Learning for Cancer Prognosis from Multi-Omics and Clinical Features
por: Xie, Gangcai, et al.
Publicado: (2019)

A canonical approach to duality transformations
por: Alvarez, Enrique, et al.
Publicado: (1994)

Supervised Regularized Canonical Correlation Analysis: integrating histologic and proteomic measurements for predicting biochemical recurrence following prostate surgery
por: Golugula, Abhishek, et al.
Publicado: (2011)

ReGeNNe: genetic pathway-based deep neural network using canonical correlation regularizer for disease prediction
por: Sharma, Divya, et al.
Publicado: (2023)

Potential Use of Human Stem Cell–Derived Intestinal Organoids to Study Inflammatory Bowel Diseases
por: Dotti, Isabella, et al.
Publicado: (2018)

inMTSCCA: An Integrated Multi-task Sparse Canonical Correlation Analysis for Multi-omic Brain Imaging Genetics
por: Du, Lei, et al.
Publicado: (2023)

A dropout-regularized classifier development approach optimized for precision medicine test discovery from omics data
por: Roder, Joanna, et al.
Publicado: (2019)

Multi-view manifold regularized compact low-rank representation for cancer samples clustering on multi-omics data
por: Wang, Juan, et al.
Publicado: (2022)

Integrating multi-OMICS data through sparse canonical correlation analysis for the prediction of complex traits: a comparison study
por: Rodosthenous, Theodoulos, et al.
Publicado: (2020)

The Pleiotropic Effects of the Canonical Wnt Pathway in Early Development and Pluripotency
por: de Jaime-Soguero, Anchel, et al.
Publicado: (2018)

Machine Learning Representation of Loss of Eye Regularity in a Drosophila Neurodegenerative Model
por: Diez-Hermano, Sergio, et al.
Publicado: (2020)

Non-canonical behaviour in canonical theories
por: Jackiw, R
Publicado: (1969)

Cannot write session to /tmp/vufind_sessions/sess_isi5kc9nepuqrk1k4erqtp5fah