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A review of methods for addressing components of interventions in meta-analysis

Many healthcare interventions are complex, consisting of multiple, possibly interacting, components. Several methodological articles addressing complex interventions in the meta-analytical context have been published. We hereby provide an overview of methods used to evaluate the effects of complex i...

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Autores principales: Petropoulou, Maria, Efthimiou, Orestis, Rücker, Gerta, Schwarzer, Guido, Furukawa, Toshi A., Pompoli, Alessandro, Koek, Huiberdina L., Del Giovane, Cinzia, Rodondi, Nicolas, Mavridis, Dimitris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870082/
https://www.ncbi.nlm.nih.gov/pubmed/33556155
http://dx.doi.org/10.1371/journal.pone.0246631
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author Petropoulou, Maria
Efthimiou, Orestis
Rücker, Gerta
Schwarzer, Guido
Furukawa, Toshi A.
Pompoli, Alessandro
Koek, Huiberdina L.
Del Giovane, Cinzia
Rodondi, Nicolas
Mavridis, Dimitris
author_facet Petropoulou, Maria
Efthimiou, Orestis
Rücker, Gerta
Schwarzer, Guido
Furukawa, Toshi A.
Pompoli, Alessandro
Koek, Huiberdina L.
Del Giovane, Cinzia
Rodondi, Nicolas
Mavridis, Dimitris
author_sort Petropoulou, Maria
collection PubMed
description Many healthcare interventions are complex, consisting of multiple, possibly interacting, components. Several methodological articles addressing complex interventions in the meta-analytical context have been published. We hereby provide an overview of methods used to evaluate the effects of complex interventions with meta-analytical models. We summarized the methodology, highlighted new developments, and described the benefits, drawbacks, and potential challenges of each identified method. We expect meta-analytical methods focusing on components of several multicomponent interventions to become increasingly popular due to recently developed, easy-to-use, software tools that can be used to conduct the relevant analyses. The different meta-analytical methods are illustrated through two examples comparing psychotherapies for panic disorder.
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spelling pubmed-78700822021-02-11 A review of methods for addressing components of interventions in meta-analysis Petropoulou, Maria Efthimiou, Orestis Rücker, Gerta Schwarzer, Guido Furukawa, Toshi A. Pompoli, Alessandro Koek, Huiberdina L. Del Giovane, Cinzia Rodondi, Nicolas Mavridis, Dimitris PLoS One Research Article Many healthcare interventions are complex, consisting of multiple, possibly interacting, components. Several methodological articles addressing complex interventions in the meta-analytical context have been published. We hereby provide an overview of methods used to evaluate the effects of complex interventions with meta-analytical models. We summarized the methodology, highlighted new developments, and described the benefits, drawbacks, and potential challenges of each identified method. We expect meta-analytical methods focusing on components of several multicomponent interventions to become increasingly popular due to recently developed, easy-to-use, software tools that can be used to conduct the relevant analyses. The different meta-analytical methods are illustrated through two examples comparing psychotherapies for panic disorder. Public Library of Science 2021-02-08 /pmc/articles/PMC7870082/ /pubmed/33556155 http://dx.doi.org/10.1371/journal.pone.0246631 Text en © 2021 Petropoulou et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Petropoulou, Maria
Efthimiou, Orestis
Rücker, Gerta
Schwarzer, Guido
Furukawa, Toshi A.
Pompoli, Alessandro
Koek, Huiberdina L.
Del Giovane, Cinzia
Rodondi, Nicolas
Mavridis, Dimitris
A review of methods for addressing components of interventions in meta-analysis
title A review of methods for addressing components of interventions in meta-analysis
title_full A review of methods for addressing components of interventions in meta-analysis
title_fullStr A review of methods for addressing components of interventions in meta-analysis
title_full_unstemmed A review of methods for addressing components of interventions in meta-analysis
title_short A review of methods for addressing components of interventions in meta-analysis
title_sort review of methods for addressing components of interventions in meta-analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870082/
https://www.ncbi.nlm.nih.gov/pubmed/33556155
http://dx.doi.org/10.1371/journal.pone.0246631
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