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Traumatic dislocation of middle ear ossicles: A new computed tomography classification predicting hearing outcome

OBJECTIVES: To assess the feasibility of radiologic measurements and find out whether hearing outcome could be predicted based on computer tomography (CT) scan evaluation in patients with temporal bone fractures and suspected ossicular joint dislocation. METHODS: We assessed 4002 temporal bone CT sc...

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Autores principales: Mantokoudis, Georgios, Schläpfer, Njima, Kellinghaus, Manuel, Hakim, Arsany, von Werdt, Moritz, Caversaccio, Marco D., Wagner, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870152/
https://www.ncbi.nlm.nih.gov/pubmed/33556107
http://dx.doi.org/10.1371/journal.pone.0245796
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author Mantokoudis, Georgios
Schläpfer, Njima
Kellinghaus, Manuel
Hakim, Arsany
von Werdt, Moritz
Caversaccio, Marco D.
Wagner, Franca
author_facet Mantokoudis, Georgios
Schläpfer, Njima
Kellinghaus, Manuel
Hakim, Arsany
von Werdt, Moritz
Caversaccio, Marco D.
Wagner, Franca
author_sort Mantokoudis, Georgios
collection PubMed
description OBJECTIVES: To assess the feasibility of radiologic measurements and find out whether hearing outcome could be predicted based on computer tomography (CT) scan evaluation in patients with temporal bone fractures and suspected ossicular joint dislocation. METHODS: We assessed 4002 temporal bone CT scans and identified 34 patients with reported ossicular joint dislocation due to trauma. We excluded those with no proven traumatic ossicular dislocation in CT scan and patients with bilateral temporal bone fractures. We measured four parameters such as malleus-incus axis distance, malleus-incus angle at midpoints, malleus- incus axis angle and ossicular joint space. The contralateral healthy side served as its own control. Hearing outcome 1–3 months after the index visit was analyzed. We assessed diagnostic accuracy and performed a logistic regression using radiologic measurement parameters for outcome prediction of conductive hearing loss (defined as >20dB air-bone gap). RESULTS: We found excellent inter-rater agreement on the measurement of axis deviation between incus and malleus in CT scans (interclass correlation coefficient 0.81). The larger the deviation of incus and malleus axis, the higher probability of poor hearing outcome (odds ratio (OR) 2.67 per 0.1mm, p = .006). A cut-off value for the axis deviation of 0.25mm showed a sensitivity of 0.778 and a specificity of 0.94 (p < .001) for discrimination between poor and good hearing outcome in terms of conductive hearing loss. CONCLUSION: Adequate assessment of high resolution CT scans of temporal bone in which ossicular chain dislocation had occurred after trauma was feasible. Axis deviations of the incus and the malleus were strongly predictive for poor hearing outcome in terms of air conduction 1–3 months after trauma. We propose a 3-level classification system for hearing outcome prediction based on radiologic measures.
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spelling pubmed-78701522021-02-11 Traumatic dislocation of middle ear ossicles: A new computed tomography classification predicting hearing outcome Mantokoudis, Georgios Schläpfer, Njima Kellinghaus, Manuel Hakim, Arsany von Werdt, Moritz Caversaccio, Marco D. Wagner, Franca PLoS One Research Article OBJECTIVES: To assess the feasibility of radiologic measurements and find out whether hearing outcome could be predicted based on computer tomography (CT) scan evaluation in patients with temporal bone fractures and suspected ossicular joint dislocation. METHODS: We assessed 4002 temporal bone CT scans and identified 34 patients with reported ossicular joint dislocation due to trauma. We excluded those with no proven traumatic ossicular dislocation in CT scan and patients with bilateral temporal bone fractures. We measured four parameters such as malleus-incus axis distance, malleus-incus angle at midpoints, malleus- incus axis angle and ossicular joint space. The contralateral healthy side served as its own control. Hearing outcome 1–3 months after the index visit was analyzed. We assessed diagnostic accuracy and performed a logistic regression using radiologic measurement parameters for outcome prediction of conductive hearing loss (defined as >20dB air-bone gap). RESULTS: We found excellent inter-rater agreement on the measurement of axis deviation between incus and malleus in CT scans (interclass correlation coefficient 0.81). The larger the deviation of incus and malleus axis, the higher probability of poor hearing outcome (odds ratio (OR) 2.67 per 0.1mm, p = .006). A cut-off value for the axis deviation of 0.25mm showed a sensitivity of 0.778 and a specificity of 0.94 (p < .001) for discrimination between poor and good hearing outcome in terms of conductive hearing loss. CONCLUSION: Adequate assessment of high resolution CT scans of temporal bone in which ossicular chain dislocation had occurred after trauma was feasible. Axis deviations of the incus and the malleus were strongly predictive for poor hearing outcome in terms of air conduction 1–3 months after trauma. We propose a 3-level classification system for hearing outcome prediction based on radiologic measures. Public Library of Science 2021-02-08 /pmc/articles/PMC7870152/ /pubmed/33556107 http://dx.doi.org/10.1371/journal.pone.0245796 Text en © 2021 Mantokoudis et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Mantokoudis, Georgios
Schläpfer, Njima
Kellinghaus, Manuel
Hakim, Arsany
von Werdt, Moritz
Caversaccio, Marco D.
Wagner, Franca
Traumatic dislocation of middle ear ossicles: A new computed tomography classification predicting hearing outcome
title Traumatic dislocation of middle ear ossicles: A new computed tomography classification predicting hearing outcome
title_full Traumatic dislocation of middle ear ossicles: A new computed tomography classification predicting hearing outcome
title_fullStr Traumatic dislocation of middle ear ossicles: A new computed tomography classification predicting hearing outcome
title_full_unstemmed Traumatic dislocation of middle ear ossicles: A new computed tomography classification predicting hearing outcome
title_short Traumatic dislocation of middle ear ossicles: A new computed tomography classification predicting hearing outcome
title_sort traumatic dislocation of middle ear ossicles: a new computed tomography classification predicting hearing outcome
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870152/
https://www.ncbi.nlm.nih.gov/pubmed/33556107
http://dx.doi.org/10.1371/journal.pone.0245796
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