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Malignant adenomyoepithelioma of the breast: A case report

RATIONALE: Adenomyoepithelioma (AME) is a rare biphasic tumor consisting of epithelial and Myoepithelial cell. Most of the AME is benign, and only a few will progress to malignancy, Here, we report a case of low-grade malignant adenomyoepithelioma, and review the related literature, in a bid to inve...

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Autores principales: Zhang, Zhihao, Wang, Yueyuan, Xie, Xiao, Peng, Jingyu, Hong, Jinghui, Bi, Lirong, Yang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870234/
https://www.ncbi.nlm.nih.gov/pubmed/33592899
http://dx.doi.org/10.1097/MD.0000000000024461
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author Zhang, Zhihao
Wang, Yueyuan
Xie, Xiao
Peng, Jingyu
Hong, Jinghui
Bi, Lirong
Yang, Ming
author_facet Zhang, Zhihao
Wang, Yueyuan
Xie, Xiao
Peng, Jingyu
Hong, Jinghui
Bi, Lirong
Yang, Ming
author_sort Zhang, Zhihao
collection PubMed
description RATIONALE: Adenomyoepithelioma (AME) is a rare biphasic tumor consisting of epithelial and Myoepithelial cell. Most of the AME is benign, and only a few will progress to malignancy, Here, we report a case of low-grade malignant adenomyoepithelioma, and review the related literature, in a bid to investigate its clinical and pathological features and thus, enhance our understanding of this tumor. PATIENT CONCERNS: A 64-year-old woman visited our hospital with a 1-year history of a painless mass in her left breast. Physical examination revealed a palpable painless mass, measuring approximately 4.5 cm, in the left breast. DIAGNOSIS: Histological examination confirmed the diagnosis of malignant adenomyoepithelioma INTERVENTIONS: The patient underwent local excision of the mass, with frozen section analysis revealing ductal carcinoma in situ. Mastectomy and sentinel lymph node biopsy were then performed. OUTCOMES: We conducted a one-year follow-up, and relapse was not observed. LESSONS: Treatment of AME remains controversial owing to the lack of high volume data and absence of prospective studies. Simple mastectomy is an acceptable treatment of this tumor.
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spelling pubmed-78702342021-02-10 Malignant adenomyoepithelioma of the breast: A case report Zhang, Zhihao Wang, Yueyuan Xie, Xiao Peng, Jingyu Hong, Jinghui Bi, Lirong Yang, Ming Medicine (Baltimore) 5700 RATIONALE: Adenomyoepithelioma (AME) is a rare biphasic tumor consisting of epithelial and Myoepithelial cell. Most of the AME is benign, and only a few will progress to malignancy, Here, we report a case of low-grade malignant adenomyoepithelioma, and review the related literature, in a bid to investigate its clinical and pathological features and thus, enhance our understanding of this tumor. PATIENT CONCERNS: A 64-year-old woman visited our hospital with a 1-year history of a painless mass in her left breast. Physical examination revealed a palpable painless mass, measuring approximately 4.5 cm, in the left breast. DIAGNOSIS: Histological examination confirmed the diagnosis of malignant adenomyoepithelioma INTERVENTIONS: The patient underwent local excision of the mass, with frozen section analysis revealing ductal carcinoma in situ. Mastectomy and sentinel lymph node biopsy were then performed. OUTCOMES: We conducted a one-year follow-up, and relapse was not observed. LESSONS: Treatment of AME remains controversial owing to the lack of high volume data and absence of prospective studies. Simple mastectomy is an acceptable treatment of this tumor. Lippincott Williams & Wilkins 2021-02-05 /pmc/articles/PMC7870234/ /pubmed/33592899 http://dx.doi.org/10.1097/MD.0000000000024461 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 5700
Zhang, Zhihao
Wang, Yueyuan
Xie, Xiao
Peng, Jingyu
Hong, Jinghui
Bi, Lirong
Yang, Ming
Malignant adenomyoepithelioma of the breast: A case report
title Malignant adenomyoepithelioma of the breast: A case report
title_full Malignant adenomyoepithelioma of the breast: A case report
title_fullStr Malignant adenomyoepithelioma of the breast: A case report
title_full_unstemmed Malignant adenomyoepithelioma of the breast: A case report
title_short Malignant adenomyoepithelioma of the breast: A case report
title_sort malignant adenomyoepithelioma of the breast: a case report
topic 5700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870234/
https://www.ncbi.nlm.nih.gov/pubmed/33592899
http://dx.doi.org/10.1097/MD.0000000000024461
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