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Comparison of the antihypertensive efficacy of morning and bedtime dosing on reducing morning blood pressure surge: A protocol for systemic review and meta-analysis

BACKGROUND: It is well known that morning blood pressure surge increases the risk of myocardial events in the first several hours post-awakening. This meta-analysis was performed to compare the antihypertensive efficacy of morning and bedtime dosing on decreasing morning blood pressure surge. METHOD...

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Autores principales: Zhang, Peng, Jin, Mei-Ying, Song, Xu-Yu, Wang, Zhao, Jiang, Yue-Hua, Yang, Chuan-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870267/
https://www.ncbi.nlm.nih.gov/pubmed/33592863
http://dx.doi.org/10.1097/MD.0000000000024127
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author Zhang, Peng
Jin, Mei-Ying
Song, Xu-Yu
Wang, Zhao
Jiang, Yue-Hua
Yang, Chuan-Hua
author_facet Zhang, Peng
Jin, Mei-Ying
Song, Xu-Yu
Wang, Zhao
Jiang, Yue-Hua
Yang, Chuan-Hua
author_sort Zhang, Peng
collection PubMed
description BACKGROUND: It is well known that morning blood pressure surge increases the risk of myocardial events in the first several hours post-awakening. This meta-analysis was performed to compare the antihypertensive efficacy of morning and bedtime dosing on decreasing morning blood pressure surge. METHODS: Articles in 4 databases about clinical trials of ingestion time of antihypertensive drugs were searched and performed a meta-analysis to evaluate the different effects on morning blood pressure and absolute blood pressure (BP) reduction from baseline of between bedtime administration (experimental group) and morning awaking administration (control group). RESULTS: The aim of this study is to compare the antihypertensive efficacy of morning and bedtime dosing on decreasing morning blood pressure surge. CONCLUSIONS: The bedtime will provide evidence support for clinicians and patients for reducing morning blood pressure surge. ETHICS AND DISSEMINATION: This study does not require ethical approval.
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spelling pubmed-78702672021-02-10 Comparison of the antihypertensive efficacy of morning and bedtime dosing on reducing morning blood pressure surge: A protocol for systemic review and meta-analysis Zhang, Peng Jin, Mei-Ying Song, Xu-Yu Wang, Zhao Jiang, Yue-Hua Yang, Chuan-Hua Medicine (Baltimore) 3400 BACKGROUND: It is well known that morning blood pressure surge increases the risk of myocardial events in the first several hours post-awakening. This meta-analysis was performed to compare the antihypertensive efficacy of morning and bedtime dosing on decreasing morning blood pressure surge. METHODS: Articles in 4 databases about clinical trials of ingestion time of antihypertensive drugs were searched and performed a meta-analysis to evaluate the different effects on morning blood pressure and absolute blood pressure (BP) reduction from baseline of between bedtime administration (experimental group) and morning awaking administration (control group). RESULTS: The aim of this study is to compare the antihypertensive efficacy of morning and bedtime dosing on decreasing morning blood pressure surge. CONCLUSIONS: The bedtime will provide evidence support for clinicians and patients for reducing morning blood pressure surge. ETHICS AND DISSEMINATION: This study does not require ethical approval. Lippincott Williams & Wilkins 2021-02-05 /pmc/articles/PMC7870267/ /pubmed/33592863 http://dx.doi.org/10.1097/MD.0000000000024127 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 3400
Zhang, Peng
Jin, Mei-Ying
Song, Xu-Yu
Wang, Zhao
Jiang, Yue-Hua
Yang, Chuan-Hua
Comparison of the antihypertensive efficacy of morning and bedtime dosing on reducing morning blood pressure surge: A protocol for systemic review and meta-analysis
title Comparison of the antihypertensive efficacy of morning and bedtime dosing on reducing morning blood pressure surge: A protocol for systemic review and meta-analysis
title_full Comparison of the antihypertensive efficacy of morning and bedtime dosing on reducing morning blood pressure surge: A protocol for systemic review and meta-analysis
title_fullStr Comparison of the antihypertensive efficacy of morning and bedtime dosing on reducing morning blood pressure surge: A protocol for systemic review and meta-analysis
title_full_unstemmed Comparison of the antihypertensive efficacy of morning and bedtime dosing on reducing morning blood pressure surge: A protocol for systemic review and meta-analysis
title_short Comparison of the antihypertensive efficacy of morning and bedtime dosing on reducing morning blood pressure surge: A protocol for systemic review and meta-analysis
title_sort comparison of the antihypertensive efficacy of morning and bedtime dosing on reducing morning blood pressure surge: a protocol for systemic review and meta-analysis
topic 3400
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870267/
https://www.ncbi.nlm.nih.gov/pubmed/33592863
http://dx.doi.org/10.1097/MD.0000000000024127
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