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Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation
Hepatic ischemia and reperfusion injury is characterized by hepatocyte apoptosis, impaired autophagy, and oxidative stress. Fenofibrate, a commonly used antilipidemic drug, has been verified to exert hepatic protective effects in other cells and animal models. The purpose of this study was to identi...
Autores principales: | Zhang, Jie, Cheng, Ping, Dai, Weiqi, Ji, Jie, Wu, Liwei, Feng, Jiao, Wu, Jianye, Yu, Qiang, Li, Jingjing, Guo, Chuanyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870311/ https://www.ncbi.nlm.nih.gov/pubmed/33603777 http://dx.doi.org/10.1155/2021/6658944 |
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