Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner

The body surface area (BSA) of animals is generally estimated by multiplying the k value (constant) by the measured body weight (BW) raised to the power of 2/3 (Meeh’s formula). Computed tomography (CT) scanners generate detailed 3-dimensional (3D) images of objects, and image analysis does not depe...

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Detalles Bibliográficos
Autores principales: ITOH, Tadashi, KAWABE, Mifumi, NAGASE, Takahiko, ENDO, Katsumi, MIYOSHI, Masafumi, MIYAHARA, Kazuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2020
Materias:
Laboratory Animal Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870410/
https://www.ncbi.nlm.nih.gov/pubmed/33281128
http://dx.doi.org/10.1292/jvms.20-0525
Descripción
Sumario:The body surface area (BSA) of animals is generally estimated by multiplying the k value (constant) by the measured body weight (BW) raised to the power of 2/3 (Meeh’s formula). Computed tomography (CT) scanners generate detailed 3-dimensional (3D) images of objects, and image analysis does not depend on operator skill. Therefore, the analysis of CT images provides accurate and reproducible BSA measurements. In this study, we measured the BSA of 25 male Hartley guinea pigs from 3 to 36 weeks of age (working BW range: 0.233 to 1.160 kg) using a CT scanner and 3D analysis software. We concluded that the k value for male Hartley guinea pigs was 8.37, based on the mean k value of the 25 animals.

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