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Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner

The body surface area (BSA) of animals is generally estimated by multiplying the k value (constant) by the measured body weight (BW) raised to the power of 2/3 (Meeh’s formula). Computed tomography (CT) scanners generate detailed 3-dimensional (3D) images of objects, and image analysis does not depe...

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Autores principales: ITOH, Tadashi, KAWABE, Mifumi, NAGASE, Takahiko, ENDO, Katsumi, MIYOSHI, Masafumi, MIYAHARA, Kazuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870410/
https://www.ncbi.nlm.nih.gov/pubmed/33281128
http://dx.doi.org/10.1292/jvms.20-0525
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author ITOH, Tadashi
KAWABE, Mifumi
NAGASE, Takahiko
ENDO, Katsumi
MIYOSHI, Masafumi
MIYAHARA, Kazuro
author_facet ITOH, Tadashi
KAWABE, Mifumi
NAGASE, Takahiko
ENDO, Katsumi
MIYOSHI, Masafumi
MIYAHARA, Kazuro
author_sort ITOH, Tadashi
collection PubMed
description The body surface area (BSA) of animals is generally estimated by multiplying the k value (constant) by the measured body weight (BW) raised to the power of 2/3 (Meeh’s formula). Computed tomography (CT) scanners generate detailed 3-dimensional (3D) images of objects, and image analysis does not depend on operator skill. Therefore, the analysis of CT images provides accurate and reproducible BSA measurements. In this study, we measured the BSA of 25 male Hartley guinea pigs from 3 to 36 weeks of age (working BW range: 0.233 to 1.160 kg) using a CT scanner and 3D analysis software. We concluded that the k value for male Hartley guinea pigs was 8.37, based on the mean k value of the 25 animals.
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spelling pubmed-78704102021-02-11 Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner ITOH, Tadashi KAWABE, Mifumi NAGASE, Takahiko ENDO, Katsumi MIYOSHI, Masafumi MIYAHARA, Kazuro J Vet Med Sci Laboratory Animal Science The body surface area (BSA) of animals is generally estimated by multiplying the k value (constant) by the measured body weight (BW) raised to the power of 2/3 (Meeh’s formula). Computed tomography (CT) scanners generate detailed 3-dimensional (3D) images of objects, and image analysis does not depend on operator skill. Therefore, the analysis of CT images provides accurate and reproducible BSA measurements. In this study, we measured the BSA of 25 male Hartley guinea pigs from 3 to 36 weeks of age (working BW range: 0.233 to 1.160 kg) using a CT scanner and 3D analysis software. We concluded that the k value for male Hartley guinea pigs was 8.37, based on the mean k value of the 25 animals. The Japanese Society of Veterinary Science 2020-12-04 2021-01 /pmc/articles/PMC7870410/ /pubmed/33281128 http://dx.doi.org/10.1292/jvms.20-0525 Text en ©2021 The Japanese Society of Veterinary Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Laboratory Animal Science
ITOH, Tadashi
KAWABE, Mifumi
NAGASE, Takahiko
ENDO, Katsumi
MIYOSHI, Masafumi
MIYAHARA, Kazuro
Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner
title Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner
title_full Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner
title_fullStr Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner
title_full_unstemmed Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner
title_short Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner
title_sort body surface area measurements in male hartley guinea pigs using a computed tomography scanner
topic Laboratory Animal Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870410/
https://www.ncbi.nlm.nih.gov/pubmed/33281128
http://dx.doi.org/10.1292/jvms.20-0525
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