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Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner
The body surface area (BSA) of animals is generally estimated by multiplying the k value (constant) by the measured body weight (BW) raised to the power of 2/3 (Meeh’s formula). Computed tomography (CT) scanners generate detailed 3-dimensional (3D) images of objects, and image analysis does not depe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Veterinary Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870410/ https://www.ncbi.nlm.nih.gov/pubmed/33281128 http://dx.doi.org/10.1292/jvms.20-0525 |
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author | ITOH, Tadashi KAWABE, Mifumi NAGASE, Takahiko ENDO, Katsumi MIYOSHI, Masafumi MIYAHARA, Kazuro |
author_facet | ITOH, Tadashi KAWABE, Mifumi NAGASE, Takahiko ENDO, Katsumi MIYOSHI, Masafumi MIYAHARA, Kazuro |
author_sort | ITOH, Tadashi |
collection | PubMed |
description | The body surface area (BSA) of animals is generally estimated by multiplying the k value (constant) by the measured body weight (BW) raised to the power of 2/3 (Meeh’s formula). Computed tomography (CT) scanners generate detailed 3-dimensional (3D) images of objects, and image analysis does not depend on operator skill. Therefore, the analysis of CT images provides accurate and reproducible BSA measurements. In this study, we measured the BSA of 25 male Hartley guinea pigs from 3 to 36 weeks of age (working BW range: 0.233 to 1.160 kg) using a CT scanner and 3D analysis software. We concluded that the k value for male Hartley guinea pigs was 8.37, based on the mean k value of the 25 animals. |
format | Online Article Text |
id | pubmed-7870410 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Japanese Society of Veterinary Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-78704102021-02-11 Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner ITOH, Tadashi KAWABE, Mifumi NAGASE, Takahiko ENDO, Katsumi MIYOSHI, Masafumi MIYAHARA, Kazuro J Vet Med Sci Laboratory Animal Science The body surface area (BSA) of animals is generally estimated by multiplying the k value (constant) by the measured body weight (BW) raised to the power of 2/3 (Meeh’s formula). Computed tomography (CT) scanners generate detailed 3-dimensional (3D) images of objects, and image analysis does not depend on operator skill. Therefore, the analysis of CT images provides accurate and reproducible BSA measurements. In this study, we measured the BSA of 25 male Hartley guinea pigs from 3 to 36 weeks of age (working BW range: 0.233 to 1.160 kg) using a CT scanner and 3D analysis software. We concluded that the k value for male Hartley guinea pigs was 8.37, based on the mean k value of the 25 animals. The Japanese Society of Veterinary Science 2020-12-04 2021-01 /pmc/articles/PMC7870410/ /pubmed/33281128 http://dx.doi.org/10.1292/jvms.20-0525 Text en ©2021 The Japanese Society of Veterinary Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Laboratory Animal Science ITOH, Tadashi KAWABE, Mifumi NAGASE, Takahiko ENDO, Katsumi MIYOSHI, Masafumi MIYAHARA, Kazuro Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner |
title | Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner |
title_full | Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner |
title_fullStr | Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner |
title_full_unstemmed | Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner |
title_short | Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner |
title_sort | body surface area measurements in male hartley guinea pigs using a computed tomography scanner |
topic | Laboratory Animal Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870410/ https://www.ncbi.nlm.nih.gov/pubmed/33281128 http://dx.doi.org/10.1292/jvms.20-0525 |
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