Cyclooxygenase activity mediates colorectal cancer cell resistance to the omega-3 polyunsaturated fatty acid eicosapentaenoic acid

PURPOSE: The naturally-occurring omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) is safe, well-tolerated and inexpensive, making it an attractive anti-cancer intervention. However, EPA has only modest anti-colorectal cancer (CRC) activity, when used alone. Both cyclooxygenase (COX) is...

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Detalles Bibliográficos
Autores principales: Volpato, Milene, Ingram, Nicola, Perry, Sarah L, Spencer, Jade, Race, Amanda D, Marshall, Catriona, Hutchinson, John M, Nicolaou, Anna, Loadman, Paul M, Coletta, P Louise, Hull, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870614/
https://www.ncbi.nlm.nih.gov/pubmed/33040178
http://dx.doi.org/10.1007/s00280-020-04157-2

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