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Single-molecule force spectroscopy reveals the dynamic strength of the hair-cell tip-link connection
The conversion of auditory and vestibular stimuli into electrical signals is initiated by force transmitted to a mechanotransduction channel through the tip link, a double stranded protein filament held together by two adhesion bonds in the middle. Although thought to form a relatively static struct...
Autores principales: | Mulhall, Eric M., Ward, Andrew, Yang, Darren, Koussa, Mounir A., Corey, David P., Wong, Wesley P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870652/ https://www.ncbi.nlm.nih.gov/pubmed/33558532 http://dx.doi.org/10.1038/s41467-021-21033-6 |
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