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General synthetic strategy for regioselective ultrafast formation of disulfide bonds in peptides and proteins
Despite six decades of efforts to synthesize peptides and proteins bearing multiple disulfide bonds, this synthetic challenge remains an unsolved problem in most targets (e.g., knotted mini proteins). Here we show a de novo general synthetic strategy for the ultrafast, high-yielding formation of two...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870662/ https://www.ncbi.nlm.nih.gov/pubmed/33558523 http://dx.doi.org/10.1038/s41467-021-21209-0 |