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Case Report: Recurrent Placental Abruption During Pregnancy in a Patient With Pseudoexstrophy

Background: Pseudoexstrophy is a rare variant of the exstrophy-epispadias complex, which comprises musculoskeletal defects associated with bladder exstrophy without any urinary tract defects. However, only a few pregnancy complications have been reported in patients with pseudoexstrophy. Case Presen...

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Autores principales: Cai, Benshuo, Guan, Yuheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870684/
https://www.ncbi.nlm.nih.gov/pubmed/33575266
http://dx.doi.org/10.3389/fmed.2021.619322
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author Cai, Benshuo
Guan, Yuheng
author_facet Cai, Benshuo
Guan, Yuheng
author_sort Cai, Benshuo
collection PubMed
description Background: Pseudoexstrophy is a rare variant of the exstrophy-epispadias complex, which comprises musculoskeletal defects associated with bladder exstrophy without any urinary tract defects. However, only a few pregnancy complications have been reported in patients with pseudoexstrophy. Case Presentation: This report presents the case of a woman with pseudoexstrophy, who survived recurrent placental abruption during the second trimester of her pregnancy. The patient presented with a bicornuate uterus and survived placental abruption twice, which may have resulted from the malformation of the uterus. Placental abruption occurred at 20 weeks during her first pregnancy, and because she was already in labor, uterine contraction was augmented until vaginal delivery was achieved. The second pregnancy, however, could not be terminated quickly enough; therefore, a cesarean section was performed to save the patient's life. Conclusions: Our study makes a significant contribution to the literature although pregnancy complications have been reported in patients with pseudoexstrophy. Our findings show that in female patients with pseudoexstrophy who are or wish to become pregnant, detailed imaging studies must be performed to identify any deformities of the pelvis or reproductive organs, in order to make a pregnancy-related risk assessment. Our experience also indicates that if surgery is inevitable, the obstetrician must be more careful when entering the abdominal cavity during the surgery to avoid secondary injury. Furthermore, the peritoneum and fascia layers must be sutured more firmly when closing the abdomen to avoid an abdominal wall hernia, because of the lack of abdominal muscle and fat tissue in such patients.
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spelling pubmed-78706842021-02-10 Case Report: Recurrent Placental Abruption During Pregnancy in a Patient With Pseudoexstrophy Cai, Benshuo Guan, Yuheng Front Med (Lausanne) Medicine Background: Pseudoexstrophy is a rare variant of the exstrophy-epispadias complex, which comprises musculoskeletal defects associated with bladder exstrophy without any urinary tract defects. However, only a few pregnancy complications have been reported in patients with pseudoexstrophy. Case Presentation: This report presents the case of a woman with pseudoexstrophy, who survived recurrent placental abruption during the second trimester of her pregnancy. The patient presented with a bicornuate uterus and survived placental abruption twice, which may have resulted from the malformation of the uterus. Placental abruption occurred at 20 weeks during her first pregnancy, and because she was already in labor, uterine contraction was augmented until vaginal delivery was achieved. The second pregnancy, however, could not be terminated quickly enough; therefore, a cesarean section was performed to save the patient's life. Conclusions: Our study makes a significant contribution to the literature although pregnancy complications have been reported in patients with pseudoexstrophy. Our findings show that in female patients with pseudoexstrophy who are or wish to become pregnant, detailed imaging studies must be performed to identify any deformities of the pelvis or reproductive organs, in order to make a pregnancy-related risk assessment. Our experience also indicates that if surgery is inevitable, the obstetrician must be more careful when entering the abdominal cavity during the surgery to avoid secondary injury. Furthermore, the peritoneum and fascia layers must be sutured more firmly when closing the abdomen to avoid an abdominal wall hernia, because of the lack of abdominal muscle and fat tissue in such patients. Frontiers Media S.A. 2021-01-26 /pmc/articles/PMC7870684/ /pubmed/33575266 http://dx.doi.org/10.3389/fmed.2021.619322 Text en Copyright © 2021 Cai and Guan. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Cai, Benshuo
Guan, Yuheng
Case Report: Recurrent Placental Abruption During Pregnancy in a Patient With Pseudoexstrophy
title Case Report: Recurrent Placental Abruption During Pregnancy in a Patient With Pseudoexstrophy
title_full Case Report: Recurrent Placental Abruption During Pregnancy in a Patient With Pseudoexstrophy
title_fullStr Case Report: Recurrent Placental Abruption During Pregnancy in a Patient With Pseudoexstrophy
title_full_unstemmed Case Report: Recurrent Placental Abruption During Pregnancy in a Patient With Pseudoexstrophy
title_short Case Report: Recurrent Placental Abruption During Pregnancy in a Patient With Pseudoexstrophy
title_sort case report: recurrent placental abruption during pregnancy in a patient with pseudoexstrophy
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870684/
https://www.ncbi.nlm.nih.gov/pubmed/33575266
http://dx.doi.org/10.3389/fmed.2021.619322
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