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Genome-Scale CRISPR-Cas9 Transcriptional Activation Screening in Metformin Resistance Related Gene of Prostate Cancer

Metformin is a classic type II diabetes drug which possesses anti-tumor properties for various cancers. However, different cancers do not respond to metformin with the same effectiveness or acquire resistance. Thus, searching for vulnerabilities of metformin-resistant prostate cancer is a promising...

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Detalles Bibliográficos
Autores principales:	Chen, Jiahong, Huang, Yaqiang, Tang, Zhenfeng, Li, Maozhang, Ling, Xiaohui, Liao, Jinxian, Zhou, Xiaobo, Fang, Shumin, Zhao, Haibo, Zhong, Weide, Yuan, Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870801/ https://www.ncbi.nlm.nih.gov/pubmed/33575255 http://dx.doi.org/10.3389/fcell.2020.616332

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