Enhancement of elastin expression by transdermal administration of sialidase isozyme Neu2

Reduction of elastin in the skin causes various skin diseases as well as wrinkles and sagging with aging. Sialidase is a hydrolase that cleaves a sialic acid residue from sialoglycoconjugate. Cleavage of sialic acid from microfibrils by the sialidase isozyme Neu1 facilitates elastic fiber assembly....

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Detalles Bibliográficos
Autores principales: Minami, Akira, Fujita, Yuka, Goto, Jun, Iuchi, Ayano, Fujita, Kosei, Mikami, Yasuyo, Shiratori, Mako, Ishii, Ami, Mitragotri, Samir, Iwao, Yasunori, Kanazawa, Hiroaki, Kurebayashi, Yuuki, Takahashi, Tadanobu, Otsubo, Tadamune, Ikeda, Kiyoshi, Suzuki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870814/
https://www.ncbi.nlm.nih.gov/pubmed/33558588
http://dx.doi.org/10.1038/s41598-021-82820-1

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