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Inhibition of cystathionine β-synthase promotes apoptosis and reduces cell proliferation in chronic myeloid leukemia
Increased endogenous hydrogen sulfide (H(2)S) level by cystathionine β-synthase (CBS) has been shown to closely relate tumorigenesis. H(2)S promotes angiogenesis, stimulates bioenergy metabolism and inhibits selective phosphatases. However, the role of CBS and H(2)S in chronic myeloid leukemia (CML)...
Autores principales: | Wang, Dan, Yang, Huan, Zhang, Yun, Hu, Rong, Hu, Dongjie, Wang, Qunxian, Liu, Yannan, Liu, Mingjing, Meng, Zijun, Zhou, Weihui, Song, Weihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870845/ https://www.ncbi.nlm.nih.gov/pubmed/33558454 http://dx.doi.org/10.1038/s41392-020-00410-5 |
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