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Inhibition of cystathionine β-synthase promotes apoptosis and reduces cell proliferation in chronic myeloid leukemia

Increased endogenous hydrogen sulfide (H(2)S) level by cystathionine β-synthase (CBS) has been shown to closely relate tumorigenesis. H(2)S promotes angiogenesis, stimulates bioenergy metabolism and inhibits selective phosphatases. However, the role of CBS and H(2)S in chronic myeloid leukemia (CML)...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Yang, Huan, Zhang, Yun, Hu, Rong, Hu, Dongjie, Wang, Qunxian, Liu, Yannan, Liu, Mingjing, Meng, Zijun, Zhou, Weihui, Song, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870845/
https://www.ncbi.nlm.nih.gov/pubmed/33558454
http://dx.doi.org/10.1038/s41392-020-00410-5

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