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Targeting autophagy enhances atezolizumab-induced mitochondria-related apoptosis in osteosarcoma
In this study, we identified the multifaceted effects of atezolizumab, a specific monoclonal antibody against PD-L1, in tumor suppression except for restoring antitumor immunity, and investigated the promising ways to improve its efficacy. Atezolizumab could inhibit the proliferation and induce immu...
Autores principales: | Liu, Zhuochao, Wang, Hongyi, Hu, Chuanzhen, Wu, Chuanlong, Wang, Jun, Hu, Fangqiong, Fu, Yucheng, Wen, Junxiang, Zhang, Weibin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870858/ https://www.ncbi.nlm.nih.gov/pubmed/33558476 http://dx.doi.org/10.1038/s41419-021-03449-6 |
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