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Genome-wide fine-mapping identifies pleiotropic and functional variants that predict many traits across global cattle populations
The difficulty in finding causative mutations has hampered their use in genomic prediction. Here, we present a methodology to fine-map potentially causal variants genome-wide by integrating the functional, evolutionary and pleiotropic information of variants using GWAS, variant clustering and Bayesi...
Autores principales: | Xiang, Ruidong, MacLeod, Iona M., Daetwyler, Hans D., de Jong, Gerben, O’Connor, Erin, Schrooten, Chris, Chamberlain, Amanda J., Goddard, Michael E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870883/ https://www.ncbi.nlm.nih.gov/pubmed/33558518 http://dx.doi.org/10.1038/s41467-021-21001-0 |
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