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BAX and SMAC regulate bistable properties of the apoptotic caspase system

The initiation of apoptosis is a core mechanism in cellular biology by which organisms control the removal of damaged or unnecessary cells. The irreversible activation of caspases is essential for apoptosis, and mathematical models have demonstrated that the process is tightly regulated by positive...

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Detalles Bibliográficos
Autores principales: McKenna, Stephanie, García-Gutiérrez, Lucía, Matallanas, David, Fey, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870884/
https://www.ncbi.nlm.nih.gov/pubmed/33558564
http://dx.doi.org/10.1038/s41598-021-82215-2