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Neuropeptide Y (NPY) intranasal delivery alleviates Machado–Joseph disease
Machado–Joseph disease (MJD) is the most common dominantly-inherited ataxia worldwide with no effective treatment to prevent, stop or alleviate its progression. Neuropeptide Y (NPY) is a neuroprotective agent widely expressed in the mammalian brain. Our previous work showed that NPY overexpression m...
Autores principales: | Duarte-Neves, Joana, Cavadas, Cláudia, Pereira de Almeida, Luís |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870889/ https://www.ncbi.nlm.nih.gov/pubmed/33558582 http://dx.doi.org/10.1038/s41598-021-82339-5 |
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