IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice

IL-36, which belongs to the IL-1 superfamily, is increasingly linked to neutrophilic inflammation. Here, we combined in vivo and in vitro approaches using primary mouse and human cells, as well as, acute and chronic mouse models of lung inflammation to provide mechanistic insight into the intercellu...

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Detalles Bibliográficos
Autores principales: Koss, Carolin K., Wohnhaas, Christian T., Baker, Jonathan R., Tilp, Cornelia, Przibilla, Michèl, Lerner, Carmen, Frey, Silvia, Keck, Martina, Williams, Cara M. M., Peter, Daniel, Ramanujam, Meera, Fine, Jay, Gantner, Florian, Thomas, Matthew, Barnes, Peter J., Donnelly, Louise E., El Kasmi, Karim C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870940/
https://www.ncbi.nlm.nih.gov/pubmed/33558616
http://dx.doi.org/10.1038/s42003-021-01703-3

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