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The mechanosensitive Piezo1 channel mediates heart mechano-chemo transduction

The beating heart possesses the intrinsic ability to adapt cardiac output to changes in mechanical load. The century-old Frank–Starling law and Anrep effect have documented that stretching the heart during diastolic filling increases its contractile force. However, the molecular mechanotransduction...

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Detalles Bibliográficos
Autores principales: Jiang, Fan, Yin, Kunlun, Wu, Kun, Zhang, Mingmin, Wang, Shiqiang, Cheng, Heping, Zhou, Zhou, Xiao, Bailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870949/
https://www.ncbi.nlm.nih.gov/pubmed/33558521
http://dx.doi.org/10.1038/s41467-021-21178-4

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