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Elevated myocardial fructose and sorbitol levels are associated with diastolic dysfunction in diabetic patients, and cardiomyocyte lipid inclusions in vitro
Diabetes is associated with cardiac metabolic disturbances and increased heart failure risk. Plasma fructose levels are elevated in diabetic patients. A direct role for fructose involvement in diabetic heart pathology has not been investigated. The goals of this study were to clinically evaluate lin...
Autores principales: | Daniels, Lorna J., Annandale, Marco, Koutsifeli, Parisa, Li, Xun, Bussey, Carol T., van Hout, Isabelle, Bunton, Richard W., Davis, Philip J., Coffey, Sean, Katare, Rajesh, Lamberts, Regis R., Delbridge, Lea M. D., Mellor, Kimberley M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870957/ https://www.ncbi.nlm.nih.gov/pubmed/33558456 http://dx.doi.org/10.1038/s41387-021-00150-7 |
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