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Mutational processes in cancer preferentially affect binding of particular transcription factors
Protein binding microarrays provide comprehensive information about the DNA binding specificities of transcription factors (TFs), and can be used to quantitatively predict the effects of DNA sequence variation on TF binding. There has also been substantial progress in dissecting the patterns of muta...
Autores principales: | Liu, Mo, Boot, Arnoud, Ng, Alvin W. T., Gordân, Raluca, Rozen, Steven G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870974/ https://www.ncbi.nlm.nih.gov/pubmed/33558557 http://dx.doi.org/10.1038/s41598-021-82910-0 |
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