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Mutational processes in cancer preferentially affect binding of particular transcription factors

Protein binding microarrays provide comprehensive information about the DNA binding specificities of transcription factors (TFs), and can be used to quantitatively predict the effects of DNA sequence variation on TF binding. There has also been substantial progress in dissecting the patterns of muta...

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Detalles Bibliográficos
Autores principales: Liu, Mo, Boot, Arnoud, Ng, Alvin W. T., Gordân, Raluca, Rozen, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870974/
https://www.ncbi.nlm.nih.gov/pubmed/33558557
http://dx.doi.org/10.1038/s41598-021-82910-0

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