Deletion of Mir223 Exacerbates Lupus Nephritis by Targeting S1pr1 in Fas(lpr/lpr) Mice

OBJECTIVE: The micro RNAs (miRNAs) and their target mRNAs are differentially expressed in various immune-mediated cells. Here, we investigated the role of Mir223 and sphingosine-1-phosphate receptor 1 (S1pr1) in the pathogenesis of systemic lupus erythematosus. METHODS: We analyzed miRNA and mRNA pr...

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Detalles Bibliográficos
Autores principales: Hiramatsu-Asano, Sumie, Sunahori-Watanabe, Katsue, Zeggar, Sonia, Katsuyama, Eri, Mukai, Tomoyuki, Morita, Yoshitaka, Wada, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871001/
https://www.ncbi.nlm.nih.gov/pubmed/33574820
http://dx.doi.org/10.3389/fimmu.2020.616141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871001/
https://www.ncbi.nlm.nih.gov/pubmed/33574820
http://dx.doi.org/10.3389/fimmu.2020.616141

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