Cargando…
Deletion of Mir223 Exacerbates Lupus Nephritis by Targeting S1pr1 in Fas(lpr/lpr) Mice
OBJECTIVE: The micro RNAs (miRNAs) and their target mRNAs are differentially expressed in various immune-mediated cells. Here, we investigated the role of Mir223 and sphingosine-1-phosphate receptor 1 (S1pr1) in the pathogenesis of systemic lupus erythematosus. METHODS: We analyzed miRNA and mRNA pr...
Autores principales: | Hiramatsu-Asano, Sumie, Sunahori-Watanabe, Katsue, Zeggar, Sonia, Katsuyama, Eri, Mukai, Tomoyuki, Morita, Yoshitaka, Wada, Jun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871001/ https://www.ncbi.nlm.nih.gov/pubmed/33574820 http://dx.doi.org/10.3389/fimmu.2020.616141 |
Ejemplares similares
-
Regulation of Cathepsin E gene expression by the transcription factor Kaiso in MRL/lpr mice derived CD4+ T cells
por: Hiramatsu, Sumie, et al.
Publicado: (2019) -
Anti-high Mobility Group Box 1 Antibody Ameliorates Albuminuria in MRL/lpr Lupus-Prone Mice
por: Watanabe, Haruki, et al.
Publicado: (2017) -
Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Fas(lpr) Mice
por: Nagasu, Akiko, et al.
Publicado: (2019) -
The role of B cells in lpr/lpr-induced autoimmunity
Publicado: (1994) -
Murine lupus is neutrophil elastase-independent in the MRL.Fas(lpr) model
por: Gordon, Rachael A., et al.
Publicado: (2020)