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Successful electroconvulsive therapy for depression in a man with cerebral amyloid angiopathy

Cerebral amyloid angiopathy (CAA) is a condition characterised by accumulation of amyloid beta protein (Aβ) in the wall of cerebral blood vessels which increases the risk of intracranial haemorrhage and contributes to cognitive impairment. We describe the case of a man around the age of 70 with ‘pro...

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Autores principales: Schurgers, Geert, Arts, Baer M G, Postma, Alida A, de Kort, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871242/
https://www.ncbi.nlm.nih.gov/pubmed/33547125
http://dx.doi.org/10.1136/bcr-2020-238922
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author Schurgers, Geert
Arts, Baer M G
Postma, Alida A
de Kort, Anna
author_facet Schurgers, Geert
Arts, Baer M G
Postma, Alida A
de Kort, Anna
author_sort Schurgers, Geert
collection PubMed
description Cerebral amyloid angiopathy (CAA) is a condition characterised by accumulation of amyloid beta protein (Aβ) in the wall of cerebral blood vessels which increases the risk of intracranial haemorrhage and contributes to cognitive impairment. We describe the case of a man around the age of 70 with ‘probable’ CAA according to the modified Boston criteria and severe depression whose depression was treated successfully with electroconvulsive therapy (ECT). To the best of our knowledge, there are no earlier published reports of ECT in a patient with CAA. We briefly discuss possible safety measures for these patients, the impact of ECT on cognition in CAA and a possible influence of ECT on Aβ clearance.
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spelling pubmed-78712422021-02-18 Successful electroconvulsive therapy for depression in a man with cerebral amyloid angiopathy Schurgers, Geert Arts, Baer M G Postma, Alida A de Kort, Anna BMJ Case Rep Case Report Cerebral amyloid angiopathy (CAA) is a condition characterised by accumulation of amyloid beta protein (Aβ) in the wall of cerebral blood vessels which increases the risk of intracranial haemorrhage and contributes to cognitive impairment. We describe the case of a man around the age of 70 with ‘probable’ CAA according to the modified Boston criteria and severe depression whose depression was treated successfully with electroconvulsive therapy (ECT). To the best of our knowledge, there are no earlier published reports of ECT in a patient with CAA. We briefly discuss possible safety measures for these patients, the impact of ECT on cognition in CAA and a possible influence of ECT on Aβ clearance. BMJ Publishing Group 2021-02-05 /pmc/articles/PMC7871242/ /pubmed/33547125 http://dx.doi.org/10.1136/bcr-2020-238922 Text en © BMJ Publishing Group Limited 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Case Report
Schurgers, Geert
Arts, Baer M G
Postma, Alida A
de Kort, Anna
Successful electroconvulsive therapy for depression in a man with cerebral amyloid angiopathy
title Successful electroconvulsive therapy for depression in a man with cerebral amyloid angiopathy
title_full Successful electroconvulsive therapy for depression in a man with cerebral amyloid angiopathy
title_fullStr Successful electroconvulsive therapy for depression in a man with cerebral amyloid angiopathy
title_full_unstemmed Successful electroconvulsive therapy for depression in a man with cerebral amyloid angiopathy
title_short Successful electroconvulsive therapy for depression in a man with cerebral amyloid angiopathy
title_sort successful electroconvulsive therapy for depression in a man with cerebral amyloid angiopathy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871242/
https://www.ncbi.nlm.nih.gov/pubmed/33547125
http://dx.doi.org/10.1136/bcr-2020-238922
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