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GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation

Nucleation of microtubules (MTs) is essential for cellular activities, but its mechanism is unknown because of the difficulty involved in capturing rare stochastic events in the early stage of polymerization. Here, combining rapid flush negative stain electron microscopy (EM) and kinetic analysis, w...

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Detalles Bibliográficos
Autores principales:	Ayukawa, Rie, Iwata, Seigo, Imai, Hiroshi, Kamimura, Shinji, Hayashi, Masahito, Ngo, Kien Xuan, Minoura, Itsushi, Uchimura, Seiichi, Makino, Tsukasa, Shirouzu, Mikako, Shigematsu, Hideki, Sekimoto, Ken, Gigant, Benoît, Muto, Etsuko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871348/ https://www.ncbi.nlm.nih.gov/pubmed/33544140 http://dx.doi.org/10.1083/jcb.202007033

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