Cargando…
The effectiveness of social bubbles as part of a Covid-19 lockdown exit strategy, a modelling study
Background: During the coronavirus disease 2019 (COVID-19) lockdown, contact clustering in social bubbles may allow extending contacts beyond the household at minimal additional risk and hence has been considered as part of modified lockdown policy or a gradual lockdown exit strategy. We estimated...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871360/ https://www.ncbi.nlm.nih.gov/pubmed/33623826 http://dx.doi.org/10.12688/wellcomeopenres.16164.2 |
_version_ | 1783648993360740352 |
---|---|
author | Leng, Trystan White, Connor Hilton, Joe Kucharski, Adam Pellis, Lorenzo Stage, Helena Davies, Nicholas G. Keeling, Matt J. Flasche, Stefan |
author_facet | Leng, Trystan White, Connor Hilton, Joe Kucharski, Adam Pellis, Lorenzo Stage, Helena Davies, Nicholas G. Keeling, Matt J. Flasche, Stefan |
author_sort | Leng, Trystan |
collection | PubMed |
description | Background: During the coronavirus disease 2019 (COVID-19) lockdown, contact clustering in social bubbles may allow extending contacts beyond the household at minimal additional risk and hence has been considered as part of modified lockdown policy or a gradual lockdown exit strategy. We estimated the impact of such strategies on epidemic and mortality risk using the UK as a case study. Methods: We used an individual based model for a synthetic population similar to the UK, stratified into transmission risks from the community, within the household and from other households in the same social bubble. The base case considers a situation where non-essential shops and schools are closed, the secondary household attack rate is 20% and the initial reproduction number is 0.8. We simulate social bubble strategies (where two households form an exclusive pair) for households including children, for single occupancy households, and for all households. We test the sensitivity of results to a range of alternative model assumptions and parameters. Results: Clustering contacts outside the household into exclusive bubbles is an effective strategy of increasing contacts while limiting the associated increase in epidemic risk. In the base case, social bubbles reduced fatalities by 42% compared to an unclustered increase of contacts. We find that if all households were to form social bubbles the reproduction number would likely increase to above the epidemic threshold of R=1. Strategies allowing households with young children or single occupancy households to form social bubbles increased the reproduction number by less than 11%. The corresponding increase in mortality is proportional to the increase in the epidemic risk but is focussed in older adults irrespective of inclusion in social bubbles. Conclusions: If managed appropriately, social bubbles can be an effective way of extending contacts beyond the household while limiting the increase in epidemic risk. |
format | Online Article Text |
id | pubmed-7871360 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | F1000 Research Limited |
record_format | MEDLINE/PubMed |
spelling | pubmed-78713602021-02-22 The effectiveness of social bubbles as part of a Covid-19 lockdown exit strategy, a modelling study Leng, Trystan White, Connor Hilton, Joe Kucharski, Adam Pellis, Lorenzo Stage, Helena Davies, Nicholas G. Keeling, Matt J. Flasche, Stefan Wellcome Open Res Research Article Background: During the coronavirus disease 2019 (COVID-19) lockdown, contact clustering in social bubbles may allow extending contacts beyond the household at minimal additional risk and hence has been considered as part of modified lockdown policy or a gradual lockdown exit strategy. We estimated the impact of such strategies on epidemic and mortality risk using the UK as a case study. Methods: We used an individual based model for a synthetic population similar to the UK, stratified into transmission risks from the community, within the household and from other households in the same social bubble. The base case considers a situation where non-essential shops and schools are closed, the secondary household attack rate is 20% and the initial reproduction number is 0.8. We simulate social bubble strategies (where two households form an exclusive pair) for households including children, for single occupancy households, and for all households. We test the sensitivity of results to a range of alternative model assumptions and parameters. Results: Clustering contacts outside the household into exclusive bubbles is an effective strategy of increasing contacts while limiting the associated increase in epidemic risk. In the base case, social bubbles reduced fatalities by 42% compared to an unclustered increase of contacts. We find that if all households were to form social bubbles the reproduction number would likely increase to above the epidemic threshold of R=1. Strategies allowing households with young children or single occupancy households to form social bubbles increased the reproduction number by less than 11%. The corresponding increase in mortality is proportional to the increase in the epidemic risk but is focussed in older adults irrespective of inclusion in social bubbles. Conclusions: If managed appropriately, social bubbles can be an effective way of extending contacts beyond the household while limiting the increase in epidemic risk. F1000 Research Limited 2021-03-29 /pmc/articles/PMC7871360/ /pubmed/33623826 http://dx.doi.org/10.12688/wellcomeopenres.16164.2 Text en Copyright: © 2021 Leng T et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Leng, Trystan White, Connor Hilton, Joe Kucharski, Adam Pellis, Lorenzo Stage, Helena Davies, Nicholas G. Keeling, Matt J. Flasche, Stefan The effectiveness of social bubbles as part of a Covid-19 lockdown exit strategy, a modelling study |
title | The effectiveness of social bubbles as part of a Covid-19 lockdown exit strategy, a modelling study |
title_full | The effectiveness of social bubbles as part of a Covid-19 lockdown exit strategy, a modelling study |
title_fullStr | The effectiveness of social bubbles as part of a Covid-19 lockdown exit strategy, a modelling study |
title_full_unstemmed | The effectiveness of social bubbles as part of a Covid-19 lockdown exit strategy, a modelling study |
title_short | The effectiveness of social bubbles as part of a Covid-19 lockdown exit strategy, a modelling study |
title_sort | effectiveness of social bubbles as part of a covid-19 lockdown exit strategy, a modelling study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871360/ https://www.ncbi.nlm.nih.gov/pubmed/33623826 http://dx.doi.org/10.12688/wellcomeopenres.16164.2 |
work_keys_str_mv | AT lengtrystan theeffectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT whiteconnor theeffectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT hiltonjoe theeffectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT kucharskiadam theeffectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT pellislorenzo theeffectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT stagehelena theeffectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT daviesnicholasg theeffectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT theeffectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT keelingmattj theeffectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT flaschestefan theeffectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT lengtrystan effectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT whiteconnor effectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT hiltonjoe effectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT kucharskiadam effectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT pellislorenzo effectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT stagehelena effectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT daviesnicholasg effectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT effectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT keelingmattj effectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy AT flaschestefan effectivenessofsocialbubblesaspartofacovid19lockdownexitstrategyamodellingstudy |