Common genetic signatures of Alzheimer’s disease in Down Syndrome

Background: People with Down Syndrome (DS) are born with an extra copy of Chromosome (Chr) 21 and many of these individuals develop Alzheimer’s Disease (AD) when they age. This is due at least in part to the extra copy of the APP gene located on Chr 21. By 40 years, most people with DS have amyloid...

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Detalles Bibliográficos
Autores principales: Sharma, Ayati, Chunduri, Alisha, Gopu, Asha, Shatrowsky, Christine, Crusio, Wim E., Delprato, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871416/
https://www.ncbi.nlm.nih.gov/pubmed/33633844
http://dx.doi.org/10.12688/f1000research.27096.2

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