Cerebrospinal fluid N-224 tau helps discriminate Alzheimer’s disease from subjective cognitive decline and other dementias

BACKGROUND: Elevated cerebrospinal fluid (CSF) concentrations of total tau (T-tau) and phosphorylated tau at Thr181 (P-tau181) protein are typical of Alzheimer’s disease (AD). However, the T-tau assay measures only the mid-region of the protein, while tau in CSF is instead composed of a series of fr...

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Detalles Bibliográficos
Autores principales: Cicognola, Claudia, Hansson, Oskar, Scheltens, Philip, Kvartsberg, Hlin, Zetterberg, Henrik, Teunissen, Charlotte E., Blennow, Kaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871566/
https://www.ncbi.nlm.nih.gov/pubmed/33557920
http://dx.doi.org/10.1186/s13195-020-00756-6

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