Neurological implications of COVID-19: a review of the science and clinical guidance

COVID-19 is a significant global health burden. The pulmonary morbidity and mortality of COVID-19 is well described, however, there is mounting evidence of neurological manifestations of SARS-CoV-2, which may be of prognostic significance. This paper summarises the available evidence in order to pro...

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Autores principales: Tan, Lynn, Lin, Zhiliang Caleb, Ray, Jason, Wesselingh, Robb, Oxley, Thomas J, McFadyen, James, Kapoor, Mahima, Hutton, Elspeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871721/
https://www.ncbi.nlm.nih.gov/pubmed/33681805
http://dx.doi.org/10.1136/bmjno-2020-000101
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author Tan, Lynn
Lin, Zhiliang Caleb
Ray, Jason
Wesselingh, Robb
Oxley, Thomas J
McFadyen, James
Kapoor, Mahima
Hutton, Elspeth
author_facet Tan, Lynn
Lin, Zhiliang Caleb
Ray, Jason
Wesselingh, Robb
Oxley, Thomas J
McFadyen, James
Kapoor, Mahima
Hutton, Elspeth
author_sort Tan, Lynn
collection PubMed
description COVID-19 is a significant global health burden. The pulmonary morbidity and mortality of COVID-19 is well described, however, there is mounting evidence of neurological manifestations of SARS-CoV-2, which may be of prognostic significance. This paper summarises the available evidence in order to provide clinicians with a concise summary of the peripheral and central neurological manifestations of COVID-19, discusses specific issues regarding the management of chronic neurological disease in the context of the pandemic, and provides a summary of the thrombotic implications of the disease for the neurologist.
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spelling pubmed-78717212021-03-04 Neurological implications of COVID-19: a review of the science and clinical guidance Tan, Lynn Lin, Zhiliang Caleb Ray, Jason Wesselingh, Robb Oxley, Thomas J McFadyen, James Kapoor, Mahima Hutton, Elspeth BMJ Neurol Open Review COVID-19 is a significant global health burden. The pulmonary morbidity and mortality of COVID-19 is well described, however, there is mounting evidence of neurological manifestations of SARS-CoV-2, which may be of prognostic significance. This paper summarises the available evidence in order to provide clinicians with a concise summary of the peripheral and central neurological manifestations of COVID-19, discusses specific issues regarding the management of chronic neurological disease in the context of the pandemic, and provides a summary of the thrombotic implications of the disease for the neurologist. BMJ Publishing Group 2020-12-14 /pmc/articles/PMC7871721/ /pubmed/33681805 http://dx.doi.org/10.1136/bmjno-2020-000101 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Review
Tan, Lynn
Lin, Zhiliang Caleb
Ray, Jason
Wesselingh, Robb
Oxley, Thomas J
McFadyen, James
Kapoor, Mahima
Hutton, Elspeth
Neurological implications of COVID-19: a review of the science and clinical guidance
title Neurological implications of COVID-19: a review of the science and clinical guidance
title_full Neurological implications of COVID-19: a review of the science and clinical guidance
title_fullStr Neurological implications of COVID-19: a review of the science and clinical guidance
title_full_unstemmed Neurological implications of COVID-19: a review of the science and clinical guidance
title_short Neurological implications of COVID-19: a review of the science and clinical guidance
title_sort neurological implications of covid-19: a review of the science and clinical guidance
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871721/
https://www.ncbi.nlm.nih.gov/pubmed/33681805
http://dx.doi.org/10.1136/bmjno-2020-000101
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