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In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing coronavirus disease 2019 (COVID-19) pandemic. Understanding of the RNA virus and its interactions with host proteins could improve therapeutic interventions for COVID-19. By using icSHAPE, we determined the stru...
Autores principales: | Sun, Lei, Li, Pan, Ju, Xiaohui, Rao, Jian, Huang, Wenze, Ren, Lili, Zhang, Shaojun, Xiong, Tuanlin, Xu, Kui, Zhou, Xiaolin, Gong, Mingli, Miska, Eric, Ding, Qiang, Wang, Jianwei, Zhang, Qiangfeng Cliff |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871767/ https://www.ncbi.nlm.nih.gov/pubmed/33636127 http://dx.doi.org/10.1016/j.cell.2021.02.008 |
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