Encapsulating Polyethyleneimine-DNA Nanoplexes into PEGylated Biodegradable Microparticles Increases Transgene Expression In Vitro and Reduces Inflammatory Responses In Vivo

Encapsulating genetic material into biocompatible polymeric microparticles is a means to improving gene transfection while simultaneously decreasing the tendency for inflammatory responses; and can be advantageous in terms of delivering material directly to the lungs via aerosolization for applicati...

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Detalles Bibliográficos
Autores principales: Terry, Treniece L., Givens, Brittany E., Adamcakova-Dodd, Andrea, Thorne, Peter S., Rodgers, Victor G. J., Salem, Aliasger K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872112/
https://www.ncbi.nlm.nih.gov/pubmed/33565009
http://dx.doi.org/10.1208/s12249-021-01932-z

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