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RAD52 Adjusts Repair of Single-Strand Breaks via Reducing DNA-Damage-Promoted XRCC1/LIG3α Co-localization

Radiation sensitive 52 (RAD52) is an important factor for double-strand break repair (DSBR). However, deficiency in vertebrate/mammalian Rad52 has no apparent phenotype. The underlying mechanism remains elusive. Here, we report that RAD52 deficiency increased cell survival after camptothecin (CPT) t...

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Detalles Bibliográficos
Autores principales:	Wang, Jian, Oh, You-Take, Li, Zhentian, Dou, Juan, Tang, Siyuan, Wang, Xiang, Wang, Hongyan, Takeda, Shunichi, Wang, Ya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872142/ https://www.ncbi.nlm.nih.gov/pubmed/33440161 http://dx.doi.org/10.1016/j.celrep.2020.108625

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