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Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding

We reported that bisphenol AF (BPAF) works as an agonist for estrogen receptor (ER) ERα but as an antagonist for ERβ. Similar results were observed for bisphenol E analogs (BPE-X) such as BPE-F, BPE-Cl, and BPE-Br, each consisting of a series of a tri-halogenated methyl group CX(3) in the central al...

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Detalles Bibliográficos
Autores principales:	Liu, Xiaohui, Suyama, Keitaro, Nose, Takeru, Shimohigashi, Miki, Shimohigashi, Yasuyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872235/ https://www.ncbi.nlm.nih.gov/pubmed/33561155 http://dx.doi.org/10.1371/journal.pone.0246583

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