Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M(™) vaccination

Recently approved vaccines have already shown remarkable protection in limiting SARS-CoV-2 associated disease. However, immunologic mechanism(s) of protection, as well as how boosting alters immunity to wildtype and newly emerging strains, remain incompletely understood. Here we deeply profiled the...

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Detalles Bibliográficos
Autores principales: Gorman, Matthew J, Patel, Nita, Guebre-Xabier, Mimi, Zhu, Alex, Atyeo, Caroline, Pullen, Krista M., Loos, Carolin, Goez-Gazi, Yenny, Carrion, Ricardo, Tian, Jing-Hui, Yaun, Dansu, Bowman, Kathryn, Zhou, Bin, Maciejewski, Sonia, McGrath, Marisa E., Logue, James, Frieman, Matthew B., Montefiori, David, Mann, Colin, Schendel, Sharon, Amanat, Fatima, Krammer, Florian, Saphire, Erica Ollmann, Lauffenburger, Douglas, Greene, Ann M., Portnoff, Alyse D., Massare, Michael J., Ellingsworth, Larry, Glenn, Gregory, Smith, Gale, Alter, Galit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872351/
https://www.ncbi.nlm.nih.gov/pubmed/33564763
http://dx.doi.org/10.1101/2021.02.05.429759

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