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In vivo antigen expression regulates CD4 T cell differentiation and vaccine efficacy against Mycobacterium tuberculosis infection

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New vaccines are urgently needed against Mycobacterium tuberculosis (Mtb), which kills more than 1.4 million people each year. CD4 T cell differentiation is a key determinant of protective immunity against Mtb, but it is not fully understood how host-pathogen interactions shape individual antigen-sp...

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Detalles Bibliográficos
Autores principales:	Clemmensen, Helena Strand, Dube, Jean-Yves, McIntosh, Fiona, Rosenkrands, Ida, Jungersen, Gregers, Aagaard, Claus, Andersen, Peter, Behr, Marcel A., Mortensen, Rasmus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872352/ https://www.ncbi.nlm.nih.gov/pubmed/33564764 http://dx.doi.org/10.1101/2021.02.02.429488

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