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Signet-Ring Cell Colon Cancer in a Teenager: A Case Report

The majority of colon cancers are diagnosed in the older population, though recent trends have demonstrated an increase in younger patients. Most colon cancers are considered adenocarcinoma. There are multiple histologic subtypes with varying prognoses. Mucinous types such as signet-ring cell carcin...

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Detalles Bibliográficos
Autores principales: Somerset, Amy, Edelman, David A, Webber, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872477/
https://www.ncbi.nlm.nih.gov/pubmed/33585120
http://dx.doi.org/10.7759/cureus.12632
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author Somerset, Amy
Edelman, David A
Webber, John
author_facet Somerset, Amy
Edelman, David A
Webber, John
author_sort Somerset, Amy
collection PubMed
description The majority of colon cancers are diagnosed in the older population, though recent trends have demonstrated an increase in younger patients. Most colon cancers are considered adenocarcinoma. There are multiple histologic subtypes with varying prognoses. Mucinous types such as signet-ring cell carcinoma (SRCC) are more aggressive with poor outcomes. SRCC frequently presents with metastatic disease which contributes to its poor prognosis. It is most commonly diagnosed around age 40. SRCC of colonic origin is very rare and comprises only 1% of colorectal cancers. Rarer still is presentation in the teenaged patient, especially in the absence of any risk factors. We present a case of an 18-year-old male with colonic SRCC. The patient presented initially with vague abdominal discomfort and three weeks later was found to have a near-obstructing right-sided colon mass. He was taken to the operating room and found to have diffuse carcinomatosis. The patient underwent palliative loop ileostomy with plans for subsequent chemotherapy.
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spelling pubmed-78724772021-02-11 Signet-Ring Cell Colon Cancer in a Teenager: A Case Report Somerset, Amy Edelman, David A Webber, John Cureus Gastroenterology The majority of colon cancers are diagnosed in the older population, though recent trends have demonstrated an increase in younger patients. Most colon cancers are considered adenocarcinoma. There are multiple histologic subtypes with varying prognoses. Mucinous types such as signet-ring cell carcinoma (SRCC) are more aggressive with poor outcomes. SRCC frequently presents with metastatic disease which contributes to its poor prognosis. It is most commonly diagnosed around age 40. SRCC of colonic origin is very rare and comprises only 1% of colorectal cancers. Rarer still is presentation in the teenaged patient, especially in the absence of any risk factors. We present a case of an 18-year-old male with colonic SRCC. The patient presented initially with vague abdominal discomfort and three weeks later was found to have a near-obstructing right-sided colon mass. He was taken to the operating room and found to have diffuse carcinomatosis. The patient underwent palliative loop ileostomy with plans for subsequent chemotherapy. Cureus 2021-01-11 /pmc/articles/PMC7872477/ /pubmed/33585120 http://dx.doi.org/10.7759/cureus.12632 Text en Copyright © 2021, Somerset et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Somerset, Amy
Edelman, David A
Webber, John
Signet-Ring Cell Colon Cancer in a Teenager: A Case Report
title Signet-Ring Cell Colon Cancer in a Teenager: A Case Report
title_full Signet-Ring Cell Colon Cancer in a Teenager: A Case Report
title_fullStr Signet-Ring Cell Colon Cancer in a Teenager: A Case Report
title_full_unstemmed Signet-Ring Cell Colon Cancer in a Teenager: A Case Report
title_short Signet-Ring Cell Colon Cancer in a Teenager: A Case Report
title_sort signet-ring cell colon cancer in a teenager: a case report
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872477/
https://www.ncbi.nlm.nih.gov/pubmed/33585120
http://dx.doi.org/10.7759/cureus.12632
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