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Chronic Immune Thrombocytopenia and Hashimoto's Hypothyroidism in an Adolescent: Presentation and Implications

Immune thrombocytopenia (ITP) is a disorder characterized by immune-mediated destruction of thrombocytes leading to peripheral blood platelet count of <100 × 10^9/L. Primary ITP is a terminology used in the absence of other causes or disorders that may be associated with thrombocytopenia, i.e., i...

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Autores principales: Ibrahim, Judy, Alashqar, Mohammad, Al Zaabi, Shamma, Trad, Omar, Al Shibli, Amar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872745/
https://www.ncbi.nlm.nih.gov/pubmed/33604093
http://dx.doi.org/10.1155/2021/6649155
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author Ibrahim, Judy
Alashqar, Mohammad
Al Zaabi, Shamma
Trad, Omar
Al Shibli, Amar
author_facet Ibrahim, Judy
Alashqar, Mohammad
Al Zaabi, Shamma
Trad, Omar
Al Shibli, Amar
author_sort Ibrahim, Judy
collection PubMed
description Immune thrombocytopenia (ITP) is a disorder characterized by immune-mediated destruction of thrombocytes leading to peripheral blood platelet count of <100 × 10^9/L. Primary ITP is a terminology used in the absence of other causes or disorders that may be associated with thrombocytopenia, i.e., isolated thrombocytopenia. The term secondary ITP is used if such diseases coexist. We present here a case of a 14-year-old female diagnosed with immune thrombocytopenia. When her evaluation was not strongly supportive of primary ITP, she was screened and proved to have a concomitant Hashimoto thyroiditis. Contrary to the popular belief about secondary ITP in adult population, treatment of our patient's hypothyroidism did not improve her platelet's count, and the patient needed multiple immunosuppressive medications to improve her condition.
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spelling pubmed-78727452021-02-17 Chronic Immune Thrombocytopenia and Hashimoto's Hypothyroidism in an Adolescent: Presentation and Implications Ibrahim, Judy Alashqar, Mohammad Al Zaabi, Shamma Trad, Omar Al Shibli, Amar Case Rep Pediatr Case Report Immune thrombocytopenia (ITP) is a disorder characterized by immune-mediated destruction of thrombocytes leading to peripheral blood platelet count of <100 × 10^9/L. Primary ITP is a terminology used in the absence of other causes or disorders that may be associated with thrombocytopenia, i.e., isolated thrombocytopenia. The term secondary ITP is used if such diseases coexist. We present here a case of a 14-year-old female diagnosed with immune thrombocytopenia. When her evaluation was not strongly supportive of primary ITP, she was screened and proved to have a concomitant Hashimoto thyroiditis. Contrary to the popular belief about secondary ITP in adult population, treatment of our patient's hypothyroidism did not improve her platelet's count, and the patient needed multiple immunosuppressive medications to improve her condition. Hindawi 2021-02-01 /pmc/articles/PMC7872745/ /pubmed/33604093 http://dx.doi.org/10.1155/2021/6649155 Text en Copyright © 2021 Judy Ibrahim et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ibrahim, Judy
Alashqar, Mohammad
Al Zaabi, Shamma
Trad, Omar
Al Shibli, Amar
Chronic Immune Thrombocytopenia and Hashimoto's Hypothyroidism in an Adolescent: Presentation and Implications
title Chronic Immune Thrombocytopenia and Hashimoto's Hypothyroidism in an Adolescent: Presentation and Implications
title_full Chronic Immune Thrombocytopenia and Hashimoto's Hypothyroidism in an Adolescent: Presentation and Implications
title_fullStr Chronic Immune Thrombocytopenia and Hashimoto's Hypothyroidism in an Adolescent: Presentation and Implications
title_full_unstemmed Chronic Immune Thrombocytopenia and Hashimoto's Hypothyroidism in an Adolescent: Presentation and Implications
title_short Chronic Immune Thrombocytopenia and Hashimoto's Hypothyroidism in an Adolescent: Presentation and Implications
title_sort chronic immune thrombocytopenia and hashimoto's hypothyroidism in an adolescent: presentation and implications
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872745/
https://www.ncbi.nlm.nih.gov/pubmed/33604093
http://dx.doi.org/10.1155/2021/6649155
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