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Laparoscopic versus Open Complete Mesocolic Excision for Right Colon Cancer

RESULTS: The mean operative time was significantly longer in the LCME group than that in the OCME group with less mean intraoperative blood loss. Conversion was required in 4 patients (8.3%) in the LCME group. The use of laparoscopy increased the number of harvested lymph nodes compared to the open...

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Autores principales: Zedan, Ali, Elshiekh, Essam, Omar, Mohamed I, Raafat, Mohamad, Khallaf, Salah M., Atta, Haisam, Hussien, Marwa T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872753/
https://www.ncbi.nlm.nih.gov/pubmed/33604087
http://dx.doi.org/10.1155/2021/8859879
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author Zedan, Ali
Elshiekh, Essam
Omar, Mohamed I
Raafat, Mohamad
Khallaf, Salah M.
Atta, Haisam
Hussien, Marwa T.
author_facet Zedan, Ali
Elshiekh, Essam
Omar, Mohamed I
Raafat, Mohamad
Khallaf, Salah M.
Atta, Haisam
Hussien, Marwa T.
author_sort Zedan, Ali
collection PubMed
description RESULTS: The mean operative time was significantly longer in the LCME group than that in the OCME group with less mean intraoperative blood loss. Conversion was required in 4 patients (8.3%) in the LCME group. The use of laparoscopy increased the number of harvested lymph nodes compared to the open approach (39.81 ± 16.74 vs. 32.65 ± 12.28, respectively, P=0.010). The laparoscopic approach was associated with a shorter time interval to first flatus as well as shorter time interval to liquid and normal diet after surgery. The postoperative hospital stay was significantly shorter in the LCME group. The complication rate was slightly lower in the LCME (14.7%) than in the OCME group (27.2%) (P=0.252). The 3-year OS in the LCME group was similar to that in OCME (78.2% vs. 63.2%, respectively, P value = 0.423). The three-year DFS in the laparoscopic group was higher (74.5%) than the open group (60.0%), but did not reach statistical significance (P value = 0.266). CONCLUSIONS: In conclusion, laparoscopic CME right hemicolectomy is a technically feasible and safe procedure if surgeon expertise is present. LCME has long-term oncologic outcomes (recurrence and survival) comparable to open surgery for management of patients with stage II or III colon cancer.
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spelling pubmed-78727532021-02-17 Laparoscopic versus Open Complete Mesocolic Excision for Right Colon Cancer Zedan, Ali Elshiekh, Essam Omar, Mohamed I Raafat, Mohamad Khallaf, Salah M. Atta, Haisam Hussien, Marwa T. Int J Surg Oncol Research Article RESULTS: The mean operative time was significantly longer in the LCME group than that in the OCME group with less mean intraoperative blood loss. Conversion was required in 4 patients (8.3%) in the LCME group. The use of laparoscopy increased the number of harvested lymph nodes compared to the open approach (39.81 ± 16.74 vs. 32.65 ± 12.28, respectively, P=0.010). The laparoscopic approach was associated with a shorter time interval to first flatus as well as shorter time interval to liquid and normal diet after surgery. The postoperative hospital stay was significantly shorter in the LCME group. The complication rate was slightly lower in the LCME (14.7%) than in the OCME group (27.2%) (P=0.252). The 3-year OS in the LCME group was similar to that in OCME (78.2% vs. 63.2%, respectively, P value = 0.423). The three-year DFS in the laparoscopic group was higher (74.5%) than the open group (60.0%), but did not reach statistical significance (P value = 0.266). CONCLUSIONS: In conclusion, laparoscopic CME right hemicolectomy is a technically feasible and safe procedure if surgeon expertise is present. LCME has long-term oncologic outcomes (recurrence and survival) comparable to open surgery for management of patients with stage II or III colon cancer. Hindawi 2021-02-02 /pmc/articles/PMC7872753/ /pubmed/33604087 http://dx.doi.org/10.1155/2021/8859879 Text en Copyright © 2021 Ali Zedan et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zedan, Ali
Elshiekh, Essam
Omar, Mohamed I
Raafat, Mohamad
Khallaf, Salah M.
Atta, Haisam
Hussien, Marwa T.
Laparoscopic versus Open Complete Mesocolic Excision for Right Colon Cancer
title Laparoscopic versus Open Complete Mesocolic Excision for Right Colon Cancer
title_full Laparoscopic versus Open Complete Mesocolic Excision for Right Colon Cancer
title_fullStr Laparoscopic versus Open Complete Mesocolic Excision for Right Colon Cancer
title_full_unstemmed Laparoscopic versus Open Complete Mesocolic Excision for Right Colon Cancer
title_short Laparoscopic versus Open Complete Mesocolic Excision for Right Colon Cancer
title_sort laparoscopic versus open complete mesocolic excision for right colon cancer
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872753/
https://www.ncbi.nlm.nih.gov/pubmed/33604087
http://dx.doi.org/10.1155/2021/8859879
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