Cargando…

Hepatocellular Carcinoma Misdiagnosed as a Liver Abscess – A Story of Misdiagnosis and Long-Term Malignant Disease Control

Hepatocellular carcinoma (HCC) is the most common liver malignancy. The presentation of HCC is highly variable which can delay diagnosis. However, the early diagnosis of HCC can significantly improve prognosis. A rare presentation of a patient with a new diagnosis of HCC with sepsis is described. A...

Descripción completa

Detalles Bibliográficos
Autores principales: Mahmoud, Ahmed, Slater, Kellee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872887/
https://www.ncbi.nlm.nih.gov/pubmed/33585123
http://dx.doi.org/10.7759/cureus.12636
_version_ 1783649276985868288
author Mahmoud, Ahmed
Slater, Kellee
author_facet Mahmoud, Ahmed
Slater, Kellee
author_sort Mahmoud, Ahmed
collection PubMed
description Hepatocellular carcinoma (HCC) is the most common liver malignancy. The presentation of HCC is highly variable which can delay diagnosis. However, the early diagnosis of HCC can significantly improve prognosis. A rare presentation of a patient with a new diagnosis of HCC with sepsis is described. A 56-year-old male presented septic with abdominal pain and a background of a chronic foot infection. The septic screen identified echocardiographic evidence of vegetations on the aortic and mitral leaflets. Also, an ultrasound of the abdomen identified multiple hypoechoic lesions suspicious for liver abscesses. Multiple attempts of ultrasound-guided aspiration of liver lesions were unsuccessful and he had a tumultuous course with recurring fevers over a period of six months. The diagnosis of HCC was eventually confirmed after the lesion eroded into his anterior gastric wall which caused an upper gastrointestinal bleed. He responded well to transarterial chemoembolization (TACE) and palliative radiation therapy. At four-year follow-up and after 11 TACE procedures, he is well without liver dysfunction and independent with daily activities.
format Online
Article
Text
id pubmed-7872887
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-78728872021-02-11 Hepatocellular Carcinoma Misdiagnosed as a Liver Abscess – A Story of Misdiagnosis and Long-Term Malignant Disease Control Mahmoud, Ahmed Slater, Kellee Cureus General Surgery Hepatocellular carcinoma (HCC) is the most common liver malignancy. The presentation of HCC is highly variable which can delay diagnosis. However, the early diagnosis of HCC can significantly improve prognosis. A rare presentation of a patient with a new diagnosis of HCC with sepsis is described. A 56-year-old male presented septic with abdominal pain and a background of a chronic foot infection. The septic screen identified echocardiographic evidence of vegetations on the aortic and mitral leaflets. Also, an ultrasound of the abdomen identified multiple hypoechoic lesions suspicious for liver abscesses. Multiple attempts of ultrasound-guided aspiration of liver lesions were unsuccessful and he had a tumultuous course with recurring fevers over a period of six months. The diagnosis of HCC was eventually confirmed after the lesion eroded into his anterior gastric wall which caused an upper gastrointestinal bleed. He responded well to transarterial chemoembolization (TACE) and palliative radiation therapy. At four-year follow-up and after 11 TACE procedures, he is well without liver dysfunction and independent with daily activities. Cureus 2021-01-11 /pmc/articles/PMC7872887/ /pubmed/33585123 http://dx.doi.org/10.7759/cureus.12636 Text en Copyright © 2021, Mahmoud et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle General Surgery
Mahmoud, Ahmed
Slater, Kellee
Hepatocellular Carcinoma Misdiagnosed as a Liver Abscess – A Story of Misdiagnosis and Long-Term Malignant Disease Control
title Hepatocellular Carcinoma Misdiagnosed as a Liver Abscess – A Story of Misdiagnosis and Long-Term Malignant Disease Control
title_full Hepatocellular Carcinoma Misdiagnosed as a Liver Abscess – A Story of Misdiagnosis and Long-Term Malignant Disease Control
title_fullStr Hepatocellular Carcinoma Misdiagnosed as a Liver Abscess – A Story of Misdiagnosis and Long-Term Malignant Disease Control
title_full_unstemmed Hepatocellular Carcinoma Misdiagnosed as a Liver Abscess – A Story of Misdiagnosis and Long-Term Malignant Disease Control
title_short Hepatocellular Carcinoma Misdiagnosed as a Liver Abscess – A Story of Misdiagnosis and Long-Term Malignant Disease Control
title_sort hepatocellular carcinoma misdiagnosed as a liver abscess – a story of misdiagnosis and long-term malignant disease control
topic General Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872887/
https://www.ncbi.nlm.nih.gov/pubmed/33585123
http://dx.doi.org/10.7759/cureus.12636
work_keys_str_mv AT mahmoudahmed hepatocellularcarcinomamisdiagnosedasaliverabscessastoryofmisdiagnosisandlongtermmalignantdiseasecontrol
AT slaterkellee hepatocellularcarcinomamisdiagnosedasaliverabscessastoryofmisdiagnosisandlongtermmalignantdiseasecontrol