Iridin Prevented Against Lipopolysaccharide-Induced Inflammatory Responses of Macrophages via Inactivation of PKM2-Mediated Glycolytic Pathways

PURPOSE: Abnormal glycolysis of immune cells contributed to the development of inflammatory response. Inhibition of this Warburg phenotype could be a promising strategy for preventing various inflammatory diseases. Iridin (IRD) is a natural isoflavone, and exerts anticancer, antioxidant, and anti-in...

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Detalles Bibliográficos
Autores principales: Ying, Zhen-Hua, Li, Hui-Min, Yu, Wen-Ying, Yu, Chen-Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872898/
https://www.ncbi.nlm.nih.gov/pubmed/33574693
http://dx.doi.org/10.2147/JIR.S292244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872898/
https://www.ncbi.nlm.nih.gov/pubmed/33574693
http://dx.doi.org/10.2147/JIR.S292244

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