Herpes simplex virus-2 associated with a large fungating penile mass

A 48-year-old male with HIV/AIDS presented with an enlarging nodular lesion on the base of his penis. Histology revealed changes consistent with chronic viral infection and culture grew herpes simplex virus 2 (HSV-2). The lesion was refractory to valacyclovir and intralesional (IL) cidofovir therapy...

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Detalles Bibliográficos
Autores principales: Bowman, Max S., Lang, Ursula E., Leslie, Kieron S., Amend, Gregory, Breyer, Benjamin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Inflammation and Infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872973/
https://www.ncbi.nlm.nih.gov/pubmed/33604244
http://dx.doi.org/10.1016/j.eucr.2021.101594
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author Bowman, Max S.
Lang, Ursula E.
Leslie, Kieron S.
Amend, Gregory
Breyer, Benjamin N.
author_facet Bowman, Max S.
Lang, Ursula E.
Leslie, Kieron S.
Amend, Gregory
Breyer, Benjamin N.
author_sort Bowman, Max S.
collection PubMed
description A 48-year-old male with HIV/AIDS presented with an enlarging nodular lesion on the base of his penis. Histology revealed changes consistent with chronic viral infection and culture grew herpes simplex virus 2 (HSV-2). The lesion was refractory to valacyclovir and intralesional (IL) cidofovir therapy. Urology excised the mass and the defect was repaired primarily with good cosmetic result. Post-operative pathology confirmed HSV-2 despite the unusual appearance of the lesion consisting of nodular mass without gross ulceration.
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spelling pubmed-78729732021-02-17 Herpes simplex virus-2 associated with a large fungating penile mass Bowman, Max S. Lang, Ursula E. Leslie, Kieron S. Amend, Gregory Breyer, Benjamin N. Urol Case Rep Inflammation and Infection A 48-year-old male with HIV/AIDS presented with an enlarging nodular lesion on the base of his penis. Histology revealed changes consistent with chronic viral infection and culture grew herpes simplex virus 2 (HSV-2). The lesion was refractory to valacyclovir and intralesional (IL) cidofovir therapy. Urology excised the mass and the defect was repaired primarily with good cosmetic result. Post-operative pathology confirmed HSV-2 despite the unusual appearance of the lesion consisting of nodular mass without gross ulceration. Elsevier 2021-02-04 /pmc/articles/PMC7872973/ /pubmed/33604244 http://dx.doi.org/10.1016/j.eucr.2021.101594 Text en © 2021 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Inflammation and Infection
Bowman, Max S.
Lang, Ursula E.
Leslie, Kieron S.
Amend, Gregory
Breyer, Benjamin N.
Herpes simplex virus-2 associated with a large fungating penile mass
title Herpes simplex virus-2 associated with a large fungating penile mass
title_full Herpes simplex virus-2 associated with a large fungating penile mass
title_fullStr Herpes simplex virus-2 associated with a large fungating penile mass
title_full_unstemmed Herpes simplex virus-2 associated with a large fungating penile mass
title_short Herpes simplex virus-2 associated with a large fungating penile mass
title_sort herpes simplex virus-2 associated with a large fungating penile mass
topic Inflammation and Infection
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872973/
https://www.ncbi.nlm.nih.gov/pubmed/33604244
http://dx.doi.org/10.1016/j.eucr.2021.101594
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