Receptor-mediated endocytosis 8 (RME-8)/DNAJC13 is a novel positive modulator of autophagy and stabilizes cellular protein homeostasis

The cellular protein homeostasis (proteostasis) network responds effectively to insults. In a functional screen in C. elegans, we recently identified the gene receptor-mediated endocytosis 8 (rme-8; human ortholog: DNAJC13) as a component of the proteostasis network. Accumulation of aggregation-pron...

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Detalles Bibliográficos
Autores principales: Besemer, Anna S., Maus, Joanna, Ax, Mirjam D. A., Stein, Anna, Vo, Stella, Freese, Christian, Nalbach, Karsten, von Hilchen, Christian, Pfalzgraf, Ines F., Koziollek-Drechsler, Ingrid, Silva, Beate, Huesmann, Heike, Boukhallouk, Fatima, Florin, Luise, Kern, Andreas, Behl, Christian, Clement, Albrecht M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873018/
https://www.ncbi.nlm.nih.gov/pubmed/32322926
http://dx.doi.org/10.1007/s00018-020-03521-y

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