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Small-Conductance Ca(2+)-Activated K(+) Channels 2 in the Hypothalamic Paraventricular Nucleus Precipitates Visceral Hypersensitivity Induced by Neonatal Colorectal Distension in Rats

Visceral hypersensitivity is one of the pivotal pathophysiological features of visceral pain in irritable bowel syndrome (IBS). Small-conductance Ca(2+)-activated K(+) channel (SK) is critical for a variety of functions in the central nervous system (CNS), nonetheless, whether it is involved in the...

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Detalles Bibliográficos
Autores principales: Ji, Ning-Ning, Du, Lei, Wang, Ying, Wu, Ke, Chen, Zi-Yang, Hua, Rong, Zhang, Yong-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873043/
https://www.ncbi.nlm.nih.gov/pubmed/33584280
http://dx.doi.org/10.3389/fphar.2020.605618