Residue-Level Contact Reveals Modular Domain Interactions of PICK1 Are Driven by Both Electrostatic and Hydrophobic Forces

PICK1 is a multi-domain scaffolding protein that is uniquely comprised of both a PDZ domain and a BAR domain. While previous experiments have shown that the PDZ domain and the linker positively regulate the BAR domain and the C-terminus negatively regulates the BAR domain, the details of internal re...

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Detalles Bibliográficos
Autores principales: Stevens, Amy O., He, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873044/
https://www.ncbi.nlm.nih.gov/pubmed/33585564
http://dx.doi.org/10.3389/fmolb.2020.616135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873044/
https://www.ncbi.nlm.nih.gov/pubmed/33585564
http://dx.doi.org/10.3389/fmolb.2020.616135

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